Browse our anti-EPS15 (EPS15) Antibodies

Full name:: anti-Epidermal Growth Factor Receptor Pathway Substrate 15 Antibodies (EPS15)

On www.antibodies-online.com are 70 Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) Antibodies from 16 different suppliers available. Additionally we are shipping EPS15 Proteins (3) and EPS15 Kits (2) and many more products for this protein. A total of 80 EPS15 products are currently listed.

Synonyms:: 2410112D09Rik, AF-1P, AF1P, anon-WO0118547.85, CG16932, Dmel\\CG16932, EH1, eps-15, eps15, i31, MLLT5, RGD1307641

list all antibodies	Gene Name	GeneID	UniProt
	EPS15	2060	P42566
	EPS15	13858	P42567
	EPS15	313474
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Most Popular Reactivities for anti-EPS15 (EPS15) Antibodies

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anti-Human EPS15 Antibodies:

anti-Mouse (Murine) EPS15 Antibodies:

anti-Rat (Rattus) EPS15 Antibodies:

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Relevant Pathways for anti-EPS15 Antibodies

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Top referenced anti-EPS15 Antibodies

Human Monoclonal EPS15 Primary Antibody for IF, IP - ABIN968187 : Alvarez, Shon, Miloso, Beguinot: Structural requirements of the epidermal growth factor receptor for tyrosine phosphorylation of eps8 and eps15, substrates lacking Src SH2 homology domains. in The Journal of biological chemistry 1995 (PubMed)
Show all 5 Pubmed References
Human Monoclonal EPS15 Primary Antibody for IF, IP - ABIN968188 : Engqvist-Goldstein, Warren, Kessels, Keen, Heuser, Drubin: The actin-binding protein Hip1R associates with clathrin during early stages of endocytosis and promotes clathrin assembly in vitro. in The Journal of cell biology 2001 (PubMed)
Show all 5 Pubmed References

More Antibodies against EPS15 Interaction Partners

Human Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) interaction partners

Fcho1 (show FCHO1 Antibodies)/2Eps15/RAP-2 (show RAP2A Antibodies) ternary complexes to facilitate conformational activation of AP-2 (show GTF3A Antibodies) by the Fcho1 (show FCHO1 Antibodies)/2 interdomain linker to promote AP-2 (show GTF3A Antibodies) cargo engagement.
An interaction of Eps15 and pS227-FIP2 (show OPTN Antibodies) at the appropriate time and location in polarizing cells is necessary for proper establishment of epithelial polarity.
RAB11FIP3 (show RAB11FIP3 Antibodies) combines with Eps15 homology domain 1 to promote the endocytosis recycling of phosphorylation of epithelial growth factor receptor (show RYK Antibodies).
Together, the data indicate that a CUL3 (show CUL3 Antibodies)-SPOPL (show SPOPL Antibodies) E3 ubiquitin ligase (show MUL1 Antibodies) complex regulates endocytic trafficking and formation of multivesicular bodies by ubiquitinating and degrading EPS15 at endosomes.
identify USP9X (show USP9X Antibodies) as a novel regulator of EGFR (show EGFR Antibodies) endocytosis
over-expression of EPS15 is a potential favorable prognostic marker in breast cancer.
MLL (show MLL Antibodies)-EPS15 translocation and individual genomic copy number alterations in monozygotic infant twins are associated with acute lymphoblastic leukemia.
Ubiquitin is sufficient for Eps15 recruitment to endosomes.
Results indicate that phosphorylation of epidermal growth factor receptor pathway substrate 15 (Eps15) at Ser (show SIGLEC1 Antibodies)-796 is catalyzed by p38 (show CRK Antibodies) directly.
distinct forms of Eps15 direct EGFR (show EGFR Antibodies) to either the late endosome/lysosome for degradation (Eps15) or to the recycling endosome for transit back to the cell surface (Eps15S)

Fruit Fly (Drosophila melanogaster) Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) interaction partners

Genetic and biochemical studies of interactions with components of the endocytic machinery suggest that Eps15 has an important role in synaptic vesicle recycling and regulates recruitment of alpha-Adaptin.
Eps-15 controls synaptic vesicle membrane retrieval and synapse development.

Mouse (Murine) Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) interaction partners

Eps15 is a regulator of B-cell lymphopoiesis
a short amino-acid stretch at the carboxy-termini of the monoubiquitinated endocytic proteins Eps15 and eps15R is indispensable for their monoubiquitination
c-Cbl (show CBL Antibodies) directs EGF (show EGF Antibodies) receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15
Our results suggest that spartin (show SPG20 Antibodies) might be involved in endocytosis, vesicle trafficking, or mitogenic activity, and that impairment in one of these processes may underlie the long axonopathy in patients with Troyer syndrome.
Mouse hepatitis virus type 2 entry is mediated through clathrin-dependent but Eps15-independent endocytosis

EPS15 Antigen Profile

Antigen Summary

This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with EPS15

epidermal growth factor receptor pathway substrate 15 (EPS15) antibody
Epidermal growth factor receptor pathway substrate clone 15 (Eps-15) antibody
epidermal growth factor receptor pathway substrate 15 (eps15) antibody
epidermal growth factor receptor pathway substrate 15 (Eps15) antibody
hypothetical protein (PGTG_06574) antibody

2410112D09Rik antibody
AF-1P antibody
AF1P antibody
anon-WO0118547.85 antibody
CG16932 antibody
Dmel\\CG16932 antibody
EH1 antibody
eps-15 antibody
eps15 antibody
i31 antibody
MLLT5 antibody
RGD1307641 antibody

Protein level used designations for EPS15

ALL1 fused gene from chromosome 1 , epidermal growth factor receptor substrate 15 , protein AF-1p , CG16932-PA , CG16932-PB , CG16932-PC , CG16932-PD , Eps-15-PA , Eps-15-PB , Eps-15-PC , Eps-15-PD , Eps15 homologue 1 , epidermal growth factor receptor pathway substrate clone 15 , epidermal growth factor receptor pathway substrate 15 , epidermal growth factor receptor substrate 15-like , epidermal growth factor pathway substrate 15

GENE ID	SPECIES
2060	Homo sapiens
37961	Drosophila melanogaster
456850	Pan troglodytes
714767	Macaca mulatta
100062532	Equus caballus
100350663	Oryctolagus cuniculus
100453749	Pongo abelii
100518076	Sus scrofa
100557165	Anolis carolinensis
100603836	Nomascus leucogenys
13858	Mus musculus
313474	Rattus norvegicus
424633	Gallus gallus
475356	Canis lupus familiaris
535998	Bos taurus
10539632	Puccinia graminis f. sp. tritici CRL 75-36-700-3
100145116	Xenopus (Silurana) tropicalis
100721481	Cavia porcellus

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Show all anti-Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) Antibodies with Pubmed References