Browse our anti-Resistin (RETN) Antibodies

Rhesus Monkey Resistin (RETN) interaction partners

1. The effects of exogenous human kisspeptin-10 (KP10) were studied on three important adipokines, namely, adiponectin, leptin, and resistin in a set of four chair-restraint habituated intact adult male rhesus monkeys.

Human Resistin (RETN) interaction partners

1. Resistin - 420 mutant genotype was associated with an increased susceptibility to osteoarthritis (p = 0.001). Similarly, resistin + 299 GA + AA genotypes showed a relation with an elevated risk of knee osteoarthritis compared to GG genotype (p = 0.01). Moreover, the mutant alleles frequency was significantly high in patient group as compared to healthy individuals for both loci.

2. RETN -420C/G polymorphism is associated with type 2 diabetes mellitus and altered metabolic profile.

3. A genetic variant of resistin and serum resistin levels were associated with postoperative pain intensity.

4. High serum RETN levels are associated with metabolic syndrome.

5. In Guillain-Barre syndrome patients, serum levels of resistin were elevated and correlated with HMGB1.

6. High serum resistin levels are associated with type 2 diabetes mellitus.

7. Study reports, for the very first time, a role of resistin in invasion and chemoresistance of ovarian cancer cells. Resistin induces epithelial-to-mesenchymal transition (EMT), along with increased stemness and decreased expression of several EMT-regulating miRNAs, which provides the mechanism of its action in ovarian cancer cells.

8. Human resistin gene RETN C-420G single nucleotide polymorphism was found to be a risk factor for type 2 diabetes in Pakistani Punjabi Rajput population.

9. Association between Resistin Gene Polymorphisms and Atopic Dermatitis

10. The expression levels of resistin in blood of pulmonary tuberculosis patients were statistically greater, whereas levels of adiponectin and leptin were smaller than in controls.

11. These results indicate that IH stress down-regulates the miR-452 in adipocytes, resulting in increased levels of RETN, TNFalpha, and CCL2 mRNAs, leading to insulin resistance in SAS patients.

12. Increased RSTN expression is associated with type 2 diabetes.

13. In the group of girls with overweight or obesity, the resistin level was lower in girls with precocious puberty than in prepubertal and pubertal girls.

14. Resistin is a constituent of mid-trimester amniotic fluid of pregnancies with trisomies 13 and 18, exhibiting lower levels than those in euploid fetuses. The reduced levels of resistin in amniotic fluid may be associated with early changes in metabolic pathways and immunoinflammatory responses.

15. High plasma resistin associates with severe acute kidney injury in Puumala hantavirus infection.

16. Adiponectin but not resistin levels were associated with intensity of liver dysfunction and worse prognosis in patients with alcoholic liver disease, suggesting a potential as a prognostic biomarker.

17. In patients with peripheral arterial disease, higher levels of resistin were associated with impaired endothelial function and an increased rate of adverse cardiac events.

18. Overexpression of resistin in chondrosarcoma cells significantly enhanced VEGF-C production and lymphangiogenesis.

19. Results provide evidence that Visfatin and resistin regulate the expression levels of some miRNA involved in osteoarthritis pathogenesis and exert catabolic functions in chondrocytes via the NF-kappaB pathway.

20. Higher circulating resistin correlated with node-negative patients and longer DFS independent of Body mass index and estrogen receptor status in women with Early-onset breast cancer

Mouse (Murine) Resistin (RETN) interaction partners

1. These findings parse a role for Ca(2+) in resistin transactivation and provide support that manipulation of Serca2a-NFATc-Resistin axis might.

2. DNA methylation of adiponectin and resistin is affected by short chain fatty acids in a high fat diet

3. Resistin and TLR4 are part of a new regulatory pathway of neuronal autophagy.

4. recombinant adiponectin and resistin, at a concentration found in the cerebrospinal fluid, have opposing effects on glucose metabolism.

5. Swimming exercises delayed the progression of atherosclerosis and prevents insulin resistance, possibly by upregulating miR-492 and downregulating resistin in aortic endothelium.

6. Resistin inhibited the activation of CREB, resulting in suppression of PGC-1alpha. Importantly, overexpressing PGC-1alpha can rescue the inhibitory effects of resistin on fatty acid beta oxidation.

7. Resistin-associated VSMC dysfunction and intimal hyperplasia are related to PKCepsilon-dependent Nox activation and ROS generation

8. Resistin may enhance inflammation by cross-talking with TLR4/NF-kappaB signaling during the development of coronary arteritis in mice

9. OLI is a physiological repressor of systemic resistin release whereas FFA upregulate resistin release in vitro from adipocytes.

10. Resistin possibly acts via an intracrine pathway as an intracellular sensor, regulating the adipocyte insulin sensitivity.

11. In 3T3-L1 adipocytes, catechin and quercetin attenuated TNF-alpha-induced elevated protein carbonyls, increased proinflammatory cytokine expression (MCP-1, resistin), and decreased adiponectin.

12. Mouse Resistin has regulative effects on murine bone marrow hematopoiesis.

13. murine resistin is increased in the lungs of wild-type mice following acute ozone exposure but does not promote ozone-induced lung pathology.

14. Inhibition of miR-696 restored the triglycerides content by up to 80%, which suggests that, in C2C12 cells, resistin at least partially increases the deposition of lipids through miR-696.

15. Antiresistin RNA oligo ameliorated metabolic abnormalities and histopathology of nonalcoholic fatty liver disease through attenuating proinflammatory cytokines

16. Resistin regulates PAI-1 expression in 3T3-L1 adipocytes via Akt phosphorylation.

17. Oxidized-LDL promotes the expression and secretion of visfatin and resistin through its activation of endoplasmic reticulum stress.

18. ET type-A receptor, ERK1/2, JNKs, AKT, and JAK2, but not ET type-B receptor or p38, are necessary for the ET-1 stimulation of resistin gene expression

19. resistin is a negative regulator of SIRT1 in both human hepatoma cell line HepG2 and mouse hepatocytes.

20. Both resistin gene expression and its secretion from the epididymal adipose tissue were decreased in db/db obese mice, while the insulin-sensitizing drug rosiglitazone increased resistin production.

Pig (Porcine) Resistin (RETN) interaction partners

1. The data suggest that there is local cooperation between resistin and PPARgamma expression in the porcine ovary. Resistin significantly increased the expression of PPARgamma, whereas PPARgamma decreased resistin expression; thus, PPARgamma is a new key regulator of resistin expression and function.

2. The expression, immunolocalization and concentration of resistin in different sized ovarian follicles, was investigated.