Resistin antibody

Catalog No. ABIN1169370

Cited in 1 publication. The Rabbit Polyclonal anti-Resistin antibody (ABIN1169370) specifically detects Resistin in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for Resistin antibody (ABIN1169370)

Target: Resistin (RETN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Resistin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Resistin Antibody

Purpose: anti-Resistin (human), pAb

Specificity: Recognizes human resistin. Weakly cross-reacts with mouse resistin. Detects a band of ~10 kDa by Western blot.

Cross-Reactivity (Details): Weakly cross-reacts with mouse resistin.

Characteristics: Polyclonal Antibody. Recognizes human resistin. Weakly cross-reacts with mouse resistin. Detects a band of ~10 kDa by Western blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human resistin.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Expiry Date: 6 months

References for anti-Resistin antibody (ABIN1169370)

Cho, Youn, Chung, Kim, Lee, Yu, Park, Shin, Park: "Common genetic polymorphisms in the promoter of resistin gene are major determinants of plasma resistin concentrations in humans." in: Diabetologia, Vol. 47, Issue 3, pp. 559-65, (2004) (PubMed).

Target Details for Resistin

Target: Resistin (RETN)

Alternative Name: Resistin

Background:

Alternate Names/Synonyms: FIZZ3, Found in Inflammatory Zone 3, ADSF, Adipose Tissue-Specific Secretory Factor

Product Description: The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.

UniProt: Q9HD89

Pathways: Feeding Behaviour, Smooth Muscle Cell Migration