Resistin antibody
Quick Overview for Resistin antibody (ABIN1169368)
Target
See all Resistin (RETN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- anti-Resistin (rat), pAb
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Specificity
- Recognizes rat resistin. Weakly cross-reacts with human and mouse resistin. Detects a band of ~10 kDa by Western blot.
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Cross-Reactivity (Details)
- Weakly cross-reacts with human and mouse resistin.
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Characteristics
- Polyclonal Antibody. Recognizes rat resistin. Weakly cross-reacts with human and mouse resistin. Detects a band of ~10 kDa by Western blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
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Sterility
- 0.2 μm filtered
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Immunogen
- Recombinant rat resistin.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4.
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Preservative
- Without preservative
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Handling Advice
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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Expiry Date
- 6 months
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- Resistin (RETN)
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Alternative Name
- Resistin
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Background
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Alternate Names/Synonyms: FIZZ3, Found in Inflammatory Zone 3, ADSF, Adipose Tissue-Specific Secretory Factor
Product Description: The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
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UniProt
- Q8K4J7
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Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Target
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