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anti-Rat (Rattus) HAS1 Antibodies:
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Human Monoclonal HAS1 Primary Antibody for ICC, ELISA - ABIN969185
Stuhlmeier: Hyaluronan production in synoviocytes as a consequence of viral infections: HAS1 activation by Epstein-Barr virus and synthetic double- and single-stranded viral RNA analogs. in The Journal of biological chemistry 2008
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Human Monoclonal HAS1 Primary Antibody for ELISA, ICC - ABIN4320735
Saito, Takayama, Mizumachi, Suzuki: Lactoferrin promotes hyaluronan synthesis in human dermal fibroblasts. in Biotechnology letters 2010
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Human Polyclonal HAS1 Primary Antibody for IF (p), IHC (p) - ABIN682093
Yang, Jiang, Cai, Liu, Zhao: Hyaluronan and hyaluronan synthases expression and localization in embryonic mouse molars. in Journal of molecular histology 2016
Human Polyclonal HAS1 Primary Antibody for WB - ABIN651121
Vigetti, Genasetti, Karousou, Viola, Clerici, Bartolini, Moretto, De Luca, Hascall, Passi: Modulation of hyaluronan synthase activity in cellular membrane fractions. in The Journal of biological chemistry 2009
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Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS1 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to the hasA gene product of Streptococcus pyogenes, a glycosaminoglycan synthetase (DG42) from Xenopus laevis, and a recently described murine hyaluronan synthase.
hyaluronan synthase 1
, HA synthase 1
, Hyaluronate synthase 1
, Hyaluronic acid synthase 1
, hyaluronate synthase 1
, hyaluronic acid synthase 1