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neudesin, which may be a negative regulator of sympathetic activity, could represent a novel regulator of the development of obesity and obesity-related metabolic dysfunctions.
Intramuscular administration of NDNF ameliorates post-MI remodeling and function in mice by its abilities to reduce myocyte apoptosis and promote neovascularization.
NDNF acts as an endogenous modulator that promotes endothelial cell function and ischemia-induced revascularization through eNOS (show NOS3 Proteins)-dependent mechanisms
Neuron-derived neurotrophic factor (NENF) is an important central modulator of food intake.
identification of neudesin, a novel mouse secreted protein showing neurotrophic activity in primary cultured mouse neurons
The present findings have revealed new potential roles of neudesin in neural cell proliferation and neuronal differentiation.
Neudesin is the first extracellular heme-binding protein that shows signal transducing activity by itself. The present findings may shed new light on the function of extracellular heme-binding proteins
These findings suggest that neudesin plays a critical role in the early stage of adipocyte differentiation in which C/EBPbeta (show CEBPB Proteins) induces PPARgamma (show PPARG Proteins) and C/EBPalpha (show CEBPA Proteins) expressions, by controlling the MAPK (show MAPK1 Proteins) pathway.
Promotes matrix assembly and cell adhesiveness. Promotes neuron migration, growth and survival as well as neurite outgrowth (By similarity).
, Spinal cord injury related protein 10
, neuron-derived neurotrophic factor
, secreted protein of unknown function
, neuron derived neurotrophic factor
, spinal cord injury-related protein 10
, fibronectin type-III domain-containing protein C4orf31
, protein NDNF
, fibronectin type-III domain-containing protein C4orf31 homolog