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anti-Human Adenosine A3 Receptor Antibodies:
anti-Mouse (Murine) Adenosine A3 Receptor Antibodies:
anti-Rat (Rattus) Adenosine A3 Receptor Antibodies:
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Cow (Bovine) Polyclonal Adenosine A3 Receptor Primary Antibody for IHC, WB - ABIN2788278
Merighi, Benini, Mirandola, Gessi, Varani, Leung, Maclennan, Baraldi, Borea: Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells. in Molecular pharmacology 2007
Human Monoclonal Adenosine A3 Receptor Primary Antibody for ELISA - ABIN559797
Stamp, Hazlett, Roberts, Frampton, Highton, Hessian: Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action. in Arthritis research & therapy 2012
Dog (Canine) Polyclonal Adenosine A3 Receptor Primary Antibody for IHC (p) - ABIN271262
Ren, Lin, Cao, Yang, Lu, Liu, Chen, Yang, Tian, Wang, Li, Wang, Chen, Ji, Zhang: CD73 is associated with poor prognosis in HNSCC. in Oncotarget 2016
Cow (Bovine) Polyclonal Adenosine A3 Receptor Primary Antibody for ELISA - ABIN4278367
Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010
Protein expression of TMIGD3 and A3AR is lower in human osteosarcoma tissues than normal tissues. Mechanistically, TMIGD3 isoform 1 and A3AR commonly inhibit the PKA-Akt (show AKT1 Antibodies)-NF-kappaB (show NFKB1 Antibodies) axis.
our results demonstrated that miR (show MLXIP Antibodies)-206 has a proinflammatory role in UC by downregulating A3AR expression and activating NF-kappaB (show NFKB1 Antibodies) signalling.
these findings propose that A3AR agonist induces cell cycle arrest and apoptosis in breast cancer stem cells by inhibition of ERK1/2 and GLI-1 (show GLI1 Antibodies) cascade.
Mast cells are directly activated by contact with cancer cell membranes by a mechanism involving autocrine formation of adenosine and autocrine/paracrine signaling of the adenosine A3 receptor.
these data suggest that Cordyceps militaris hot water extracts containing cordycepin may be a promising treatment for bladder cancer via A3 adenosine receptor activation.
Differential regulation in patients with LTP (show SCP2 Antibodies)-induced anaphylaxis and those with NSAID-LTP (show SCP2 Antibodies)-induced anaphylaxis of the IFN-gamma (show IFNG Antibodies) pathway, IgG receptors, and ADORA3 might provide the pathogenic basis of their distinct responses
This study identifies human mast cell A3R as regulator of tissue remodeling gene expression in human mast cells and demonstrates a heretofore-unrecognized mode of feedback regulation that is exerted by this receptor.
This is a review of the role played by A2aR (show ADORA2A Antibodies) and A3AR in regulating cancer pathogenesis, with a focus on melanoma, and the therapeutic potential of adenosine receptors pharmacological modulation. [review]
Different agonistic behavior at adenosine A3 receptor is linked to a sub-pocket of the binding site.
There is differential expression of receptors in rheumatoid synovial tissue such that ADORA3 is expressed at significantly higher levels
mRNA for adenosine A(1), A(2A), A(2B (show ADRA2B Antibodies)), and A(3) receptors was expressed in arterioles and venules. Protein for A(1), A(2A), and A(2B (show ADRA2B Antibodies)), but not A(3), was detected in both microvessel types and was further demonstrated on vascular endothelial cells
Reduction in nephron number combined with chronic HS intake is associated with oxidative stress, chronic inflammation, and development of hypertension in mice. Absence of adenosine A3 receptor signaling was strongly protective in this novel mouse model of renal and cardiovascular disease.
Adenosine A1A receptor and adenosine A3A receptor agonists and adenosine 5'-monophosphate cause regulated hypothermia that was characterized by a drop in total energy expenditure, physical inactivity, and preference for cooler environmental temperatures, indicating a reduced body temperature set point.
A3AR knockout mice had higher survival rates following lethal doses of gamma-radiation than wild type mice.
Increased values of bone marrow parameters were found in femoral bone marrow from adenosine A3 receptor-knock out mice.
These studies reveal A3AR activation by adenosine as an endogenous anti-nociceptive pathway and support the development of A3AR agonists as novel therapeutics to treat chronic pain.
Adenosin inhibited Lipopolysaccharide-increased HIF1alpha (show HIF1A Antibodies) accumulation under both normoxic and hypoxic conditions, through activation of A1 and A3 adenosine receptors.
A3AR induces reactive oxygen species generation, possibly through activation of Nox2 (show CYBB Antibodies), with subsequent contraction of the mouse aorta.
A3 adenosine receptor inhibition improves the efficacy of hypertonic saline resuscitation.
Activation of A(1)R or A(3)R by CCPA or Cl-IB-MECA, respectively, protects cardiomyocytes from hypoxia via phosphorylation of p38 MAPK (show MAPK14 Antibodies), which is located downstream from the mitochondrial K(ATP) channel opening
Activation of macrophages by lipopolysaccharide induced down-regulation of the expression of adenosine receptor A3 mrna.
This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
adenosine receptor A3
, adenosine A3 receptor
, A3 adenosine receptor
, G-protein coupled receptor 2
, Gpcr 2