Adenosine A3 Receptor antibody (AA 85-180)

Catalog No. ABIN673629

Product Details anti-Adenosine A3 Receptor Antibody

Target: Adenosine A3 Receptor (ADORA3)

Binding Specificity: AA 85-180

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenosine A3 Receptor antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADORA3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Adenosine A3 Receptor

Target: Adenosine A3 Receptor (ADORA3)

Alternative Name: Adenosine A3 Receptor (ADORA3 Products)

Synonyms: A3AR antibody, AD026 antibody, bA552M11.5 antibody, ADORA3 antibody, 1700001D09Rik antibody, 4930578J19Rik antibody, A3R antibody, AA3R antibody, ARA3 antibody, Gpcr2 antibody, adenosine A3 receptor antibody, adenosine receptor A3 antibody, ADORA3 antibody, Adora3 antibody, LOC100603318 antibody

Background:

Isoform 2: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Isoform 1: Plays a suppressive role in osteosarcoma malignancy by inhibiting NF-kappa-B activity.

Subcellular location: Cell membrane

Synonyms: Adenosine receptor A3, ADORA3, AA3R_HUMAN

Gene ID: 140

UniProt: P0DMS8

Pathways: Hormone Transport, cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process