Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Mouse (Murine) Antibodies:
anti-Rat (Rattus) Antibodies:
Go to our pre-filtered search.
Human Monoclonal HNF1A Primary Antibody for IF, WB - ABIN968240
Frain, Swart, Monaci, Nicosia, Stämpfli, Frank, Cortese: The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domain. in Cell 1989
Show all 5 Pubmed References
Human Monoclonal HNF1A Primary Antibody for IF, WB - ABIN968241
Kritis, Ktistaki, Barda, Zannis, Talianidis: An indirect negative autoregulatory mechanism involved in hepatocyte nuclear factor-1 gene expression. in Nucleic acids research 1994
Show all 5 Pubmed References
Human Polyclonal HNF1A Primary Antibody for ICC, IF - ABIN443456
Yasui, Miyoshi, Tababe, Ishigami, Fukutomi, Imai, Isemura: Effects of oolong tea on gene expression of gluconeogenic enzymes in the mouse liver and in rat hepatoma H4IIE cells. in Journal of medicinal food 2011
Show all 2 Pubmed References
Dog (Canine) Polyclonal HNF1A Primary Antibody for ELISA - ABIN188701
Hansen, Párrizas, Jensen, Pruhova, Ek, Boj, Johansen, Maestro, Rivera, Eiberg, Andel, Lebl, Pedersen, Ferrer, Hansen: Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function. in The Journal of clinical investigation 2002
Cow (Bovine) Polyclonal HNF1A Primary Antibody for IHC, WB - ABIN2784536
Scheving, Zhang, Garcia, Wang, Stevenson, Threadgill, Russell: Epidermal growth factor receptor plays a role in the regulation of liver and plasma lipid levels in adult male mice. in American journal of physiology. Gastrointestinal and liver physiology 2014
genetic association studies in population in Japan: Data suggest that HNF1A diplotype of three genetic risk variants (SNPs rs1169288-C, rs1183910-A, rs2464196-A) may be independent risk factor for development of diabetic retinopathy resulting from poor glycemic control in normal-weight patients with type 2 diabetes in the population studied.
data suggested that the missense mutation of HNF1alpha (p.Q511L) may associate with the progression of hepatocellular carcinoma
We confirmed that the SNPs in the HNF1A were associated with higher serum ApoA1 (show APOA1 Antibodies) levels. Our results indicate that the polymorphic variability in the HNF1A locus may be a factor involving in the risk of CAD (show CAD Antibodies) and IS.
A SNP located in the HNF1A gene is associated with polycystic ovary syndrome (PCOS) among Han Chinese women. This suggested that variations in HNF1A might confer risk for PCOS
Lef1 (show LEF1 Antibodies) and Tcf1 showed oncogenic effect in colonic carcinogenesis. Cellular context of miRNAs might play important roles in carcinogenesis by altering the expression pattern of Lef/Tcfs members.
HNF1alpha, which has previously been described as a modulator of several transporters of the renal transportosome, is also a key determinant of PDZK1 (show PDZK1 Antibodies) transcription.
Results identified HNF1A/B as a good candidates to master the regulation of pancreatic differentiation, which at the protein level loses its expression in malignant ductal cells of the pancreas, suggesting its putative role as tumor suppressor in pancreatic cancer.
this study found that 20%-60% of Hepatit (show CD8A Antibodies)is C-specific CD8+ T cells were Tcf1+
Findings suggest that there are subtypes of T2DM characterized by different urinary glucose excretion and cardiovascular risk factors. SLC5A2 (show SLC5A2 Antibodies) and HNF1A mutations partially explain renal glycosuria in patients with T2DM.
Results indicate that HNF1alpha can modulate the expression of hepatitis B virus (HBV) large surface proteins to interfere virion production, and HNF1alpha is capable of limiting HBV transcription and replication by activating the NF-kappaB (show NFKB1 Antibodies) signaling.
Transcriptional analysis revealed 4 important genes involved in sphingolipid metabolism to be deregulated in HNF1A deficiency: Ormdl1 (show ORMDL1 Antibodies), sphingosine kinase-2 (show SPHK2 Antibodies), neutral ceramidase, and ceramide synthase-5 (show LASS5 Antibodies).
This is attributed in part to ineffective repression of Tcf1 expression in knockout T cells, as DNMT3a (show DNMT3A Antibodies) localizes to the Tcf7 (show TCF7 Antibodies) promoter and catalyzes its de novo methylation in early effector WT CD8 (show CD8A Antibodies)(+) T cells. These data identify DNMT3a (show DNMT3A Antibodies) as a crucial regulator of CD8 (show CD8A Antibodies)(+) early effector cell differentiation and effector versus memory fate decisions.
We identified PD-1 (show PDCD1 Antibodies) to be specifically expressed in PLZF (show ZBTB16 Antibodies)(+) ILCp and revealed that the timing and order of expression of the transcription factors NFIL3 (show NFIL3 Antibodies), ID2, and TCF-1 was critical. Importantly, induction of ILC (show CCL27 Antibodies) lineage commitment required only transient expression of NFIL3 (show NFIL3 Antibodies) prior to ID2 and TCF-1 expression.
Knockdown of MACF1 (show MACF1 Antibodies) in osteoblastic cells inhibits osteoblast differentiation through suppressing the beta-catenin (show CTNNB1 Antibodies)/TCF1-Runx2 (show RUNX2 Antibodies) axis.
this study found that virus-specific CD8 (show CD8A Antibodies)(+) T cells that sustained the T cell response during chronic viral infection are defined by, and depended on, the expression of Tcf1
data demonstrate a novel miR (show MLXIP Antibodies)-24-TCF1 pathway in controlling effector cytokine production by T cells and further suggest miR (show MLXIP Antibodies)-24 could function as a key upstream molecule regulating TCF1-mediated immune responses.
HNF1alpha plays a crucial role in hepatocyte lipid metabolism and hepatocarcinogenesis
Data show that TCF1 proteindeficiency relieved most manifestations of autoimmune lymphoproliferative syndrome (ALPS)-like phenotype, which were caused by Fas (show FAS Antibodies) protein mutation in TCF1(-/-) lpr/lpr (show FAS Antibodies) mice.
Data show that the Wnt-effector hepatocyte nuclear factor 1-alpha (Tcf1) is recruited to and triggers transcription of the Ink4/Arf tumor suppressor locus, such as as p15Ink4b, p16Ink4a and p19Arf.
pigs harboring the dominant-negative mutant human MODY3 gene showed reproducible and distinct glomerular nodules.
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas.
HNF1 homeobox A
, albumin proximal factor
, hepatic nuclear factor 1
, hepatocyte nuclear factor 1-alpha
, interferon production regulator factor
, liver-specific transcription factor LF-B1
, transcription factor 1, hepatic
, hepatic nuclear factor (HNF1)
, transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor
, hepatocyte nuclear factor 1
, transcription factor 1
, LF-B1 hepatic nuclear factor (HNF1): albumin proximal factor also TCF1
, LF-B1, hepatic nuclear factor (HNF1): albumin proximal factor, also TCF1
, Transcription factor 1 hepatic
, Transcription factor 1, hepatic
, hepatic nuclear factor-1-alpha
, hepatocyte nuclear factor 1 alpha