HNF1A antibody (N-Term)

Catalog No. ABIN2787450

The Rabbit Polyclonal anti-HNF1A antibody (ABIN2787450) specifically detects HNF1A in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Sheep, Zebrafish (Danio rerio) and Rabbit samples.

Quick Overview for HNF1A antibody (N-Term) (ABIN2787450)

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Sheep, Zebrafish (Danio rerio), Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HNF1A Antibody

Binding Specificity: N-Term

Purpose: HNF1A Antibody - N-terminal region

Sequence: HAGQGGLIEE PTGDELPTKK GRRNRFKWGP ASQQILFQAY ERQKNPSKEE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against HNF1A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNF1A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57904-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HNF1A

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Alternative Name: HNF1A

Background:

Background Information: HNF1A is required for the expression of several liver specific genes. HNF1A binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.

Gene Name: HNF1 homeobox A

Alternative Symbols: HNF1, LFB1, TCF1, HNF4A, MODY3, TCF-1, HNF-1A, IDDM20, HNF1alpha

Protein Name: Hepatocyte nuclear factor 1-alpha

Molecular Weight: 67kDa

Gene ID: 6927

NCBI Accession: NP_000536

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis