Protein Summary

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV\\; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1\\; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003

Alternative names and synonyms associated with NLR Family, Pyrin Domain Containing 11 (NLRP11)

• NLR family pyrin domain containing 11 (NLRP11) antibody

• CLR19.6 antibody
• NALP11 antibody
• NOD17 antibody
• PAN10 antibody
• PYPAF6 antibody
• Show all synonym aliases
• PYPAF7 antibody

Protein level used designations for NLRP11

NACHT, LRR and PYD containing protein 11 , NACHT, LRR and PYD domains-containing protein 11 , NACHT, leucine rich repeat and PYD containing 11 , PAAD- and NACHT-containing protein 10 , PAAD- and NACHT-containing protein 10B , PAAD-and NACHT domain-containing protein 10 , PYRIN-containing APAF1-like protein 6 , nucleotide-binding oligomerization domain protein 17 , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 11 , NLR family, pyrin domain containing 11