NLRP11 antibody (AA 420-600)

Catalog No. ABIN6144660

This Rabbit Polyclonal antibody specifically detects NLRP11 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for NLRP11 antibody (AA 420-600) (ABIN6144660)

Target: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP11 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-NLRP11 Antibody

Binding Specificity: AA 420-600

Sequence: VGFTEADVSV LQAANILLPS NTHKDRYKFI HLNVQEFCTA IAFLMAVPNY LIPSGSREYK EKREQYSDFN QVFTFIFGLL NANRRKILET SFGYQLPMVD SFKWYSVGYM KHLDRDPEKL THHMPLFYCL YENREEEFVK TIVDALMEVT VYLQSDKDMM VSLYCLDYCC HLRTLKLSVQ R

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 420-600 of human NLRP11 (NP_659444.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NLRP11

Target: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Alternative Name: NLRP11

Background: This gene is a member of the the NOD-like receptor protein (NLRP) gene family and encodes a protein with an N-terminal pyrin death (PYD) domain and nucleoside triphosphate hydrolase (NACHT) domain and a C-terminal leucine-rich repeats (LRR) region. This gene has been shown to regulate caspases in the proinflammatory signal transduction pathway and, based on studies of other members of the NLRP gene family with similar domain structure, is predicted to form part of the multiprotein inflammasome complex. Alternative splicing produces multiple transcript variants encoding distince isoforms.,NLRP11,CLR19.6,NALP11,NOD17,PAN10,PYPAF6,PYPAF7,Epigenetics & Nuclear Signaling,RNA Binding,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,NLRP11

Molecular Weight: 105 kDa/111 kDa/117 kDa

Gene ID: 204801

UniProt: P59045

Pathways: Inflammasome