Protein Summary

This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with Phosphatidylinositol Glycan Anchor Biosynthesis, Class P (PIGP)

• phosphatidylinositol glycan anchor biosynthesis class P (PIGP) antibody
• phosphatidylinositol glycan anchor biosynthesis class P (pigp) antibody
• phosphatidylinositol glycan anchor biosynthesis, class P (Pigp) antibody
• phosphatidylinositol glycan anchor biosynthesis, class P (pigp) antibody

• Dcrc antibody
• dcrc-s antibody
• Dscr5 antibody
• dsrc antibody
• Pigp antibody
• Show all synonym aliases
• wu:fc66d08 antibody
• zgc:73366 antibody

Protein level used designations for PIGP

Down syndrome critical region gene 5 , Down syndrome critical region protein 5 , Down syndrome critical region protein C , PIG-P , phosphatidylinositol N-acetylglucosaminyltransferase subunit P , phosphatidylinositol glycan, class P , phosphatidylinositol-glycan biosynthesis class P protein , phosphatidylinositol-n-acetylglucosaminyltranferase subunit , Down syndrome critical region gene c , Down syndrome critical region homolog 5 , down syndrome critical region protein 5 homolog , phosphatidylinositol glycan anchor biosynthesis, class P