Browse our Angiotensin II Type-1 Receptor Proteins (AGTR1)

Full name:: Angiotensin II Receptor, Type 1 Proteins (AGTR1)

On www.antibodies-online.com are 8 Angiotensin II Receptor, Type 1 (AGTR1) Proteins from 5 different suppliers available. Additionally we are shipping Angiotensin II Type-1 Receptor Antibodies (131) and Angiotensin II Type-1 Receptor Kits (82) and many more products for this protein. A total of 229 Angiotensin II Type-1 Receptor products are currently listed.

Synonyms:: 1810074K20Rik, AG2S, Agtr-1a, agtr1, agtr1-a, agtr1-b, agtr1.2, AGTR1A, AGTR1B, AI551199, Angtr-1a, at1, AT1-R, AT1a, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, AT3, AT₁R, HAT1R, xAT, XAT-1

list all proteins	Gene Name	GeneID	UniProt
	AGTR1	185	P30556
	AGTR1	11607	P29754
	AGTR1	81638	P29089
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Angiotensin II Type-1 Receptor Proteins (AGTR1) by Origin

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Human Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

A high level of ART1 (show ART1 Proteins) antibodies was a risk factor for allograft function in kidney transplant recipients.
we found an interaction between ACE2 and AGTR1 in structuralatrial fibrillation patients in a Chinese Han population
AGTR1 DNA hypomethylation is a risk factor for the development of hypertension. Furthermore, there is a correlation between smoking, diet, and AGTR1 DNA methylation (show HELLS Proteins) levels.
Chinese Han persons with C allele of rs9817428 in PPARG (show PPARG Proteins) gene were related to the increased risk of hypertension.
Results showed no association between genotypes and preeclampsia for polymorphisms rs5186, rs4606 in 3'UTR of genes ACVR2A (show ACVR2A Proteins), AGTR1 and RGS2 (show RGS2 Proteins) in women with preeclampsia
Association of AGTR1 single nucleotide polymorphism rs275645 and pre-eclampsia in Chinese population.
although the present study did not find any association between AGTR1 A1166C polymorphism and the risk of systemic lupus erythematosus, the presence of this polymorphism was associated with higher levels of malondialdehyde and higher concentration of neopterin
We conclude that the crosstalk between angiotensin AT1 receptor (show AGTRAP Proteins) and insulin receptor (show INSR Proteins) signaling shows a high degree of specificity, and involves Galphaq (show GNAQ Proteins) protein, and activation of distinct kinases. Thus, the BRET (show DNER Proteins)(2) technique can be used as a platform for studying molecular mechanisms of crosstalk between insulin receptor (show INSR Proteins) and 7TM receptors.
The AGTR1-mediated cell apoptosis was suppressed by overexpressing miR (show MLXIP Proteins)-1248 and inhibited protein translation of AGTR1 by miR (show MLXIP Proteins)-1248, through binding to the 3'-UTR of the AGTR1 mRNA.
AGTR1 gene, related to renin (show REN Proteins)-angiotensin system, might play momentous roles in the initiation and development of consecutive Trauma-Induced Sepsis.

Mouse (Murine) Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

the expression of AT2 (show AGTR2 Proteins) receptors was significantly increased compared to that of AT1 (show SLC33A1 Proteins) receptors upon ischemic induction.
Transforming growth factor-beta1 induces cerebrovascular dysfunction and astrogliosis through angiotensin II type 1 receptor-mediated signaling pathways
High AT1R (show AGTRAP Proteins) expression is associated with acute lung injury.
QLQX may improve diabetic cardiac function by regulating AGTR1/ TRPV1-mediated autophagy in STZ-induced diabetic mice.
Inhibition or deletion of angiotensin II type 1 receptor suppresses elastase-induced experimental abdominal aortic aneurysms.
AT1R (show AGTRAP Proteins) in antigen-specific CD8 (show CD8A Proteins)(+) T cells regulates expansion, differentiation, and function during effector and memory phases of the response against Plasmodium, which could apply to different infectious agents.
Nrf2 (show NFE2L2 Proteins)-mediated stimulation of intrarenal Renin (show REN Proteins)-angiotensin system gene expression, by which chronic hyperglycemia induces hypertension and renal injury in diabetes.
This study aimed to define whether sex chromosome complement (SCC (show CYP11A1 Proteins)) may differentially modulate sex differences in relative gene expression of basal Agtr1a, Agtr2 (show AGTR2 Proteins), and Mas1 (show MAS1 Proteins) receptors at fore/hindbrain nuclei and at medulla/cortical kidney.
The formation of liver metastasis, in a mouse model of colorectal cancer, correlated with collagen deposition in the metastatic area, which was dependent on AT1a signaling.
Perivascular Adipose Tissue Angiotensin II Type 1a Receptor Promotes Vascular Inflammation and Aneurysm formation in apolipoprotein E (show APOE Proteins)-deficient (ApoE (show APOE Proteins)(-/-)) mice.

Cow (Bovine) Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

These results identify bTREK-1 K(+) channels as a pivotal control point where ANG II (show AGT Proteins) receptor activation is transduced to depolarization-dependent Ca(2 (show CA2 Proteins)+) entry and aldosterone secretion.
Angiotensin II (ANGII) inhibits adrenocortical cell KCNK2 in an ATP dependent, PLC/PKC independent manner.

Xenopus laevis Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

transcripts for the ANGII receptor type 1 (ATR1) were detected in lungs of Xenopus laevis

Rabbit Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

Ang II (show AGT Proteins) increase HTFs proliferation, migration, and phenotype transition, suggesting that Ang II (show AGT Proteins) may play a role in wound healing after trabeculectomy.
Renal AT1R expression was increased by approximately 67% and AT2R (show AGTR2 Proteins) expression was decreased by approximately 87% in rabbits with heart failure; however, kidneys from denervated rabbits with heart failure showed a near normalization in the expression of these receptors.
Atrial fibrillation induces myocardial fibrosis through angiotensin II type 1 receptor-specific Arkadia (show RNF111 Proteins)-mediated downregulation of Smad7 (show SMAD7 Proteins).
Following inflammation in the femoral artery angiotensin AT1 receptors are activated along with thromboxane receptors.
Corneal cells express ACE (show ACE Proteins), AT(1) and AT(2)receptors. ACE (show ACE Proteins) inhibitor enalapril decreased corneal angiogenesis in VEGF (show VEGFA Proteins)-induced corneal neovascularization. ACE (show ACE Proteins) inhibitors may be novel therapy to treat corneal angiogenesis.
investigated whether oxidant stress plays a role in Ang II-induced AT1R upregulation and its relationship to the transcription factor activator protein 1 (AP1) in CHF rabbits and in the CATHa neuronal cell line

Guinea Pig Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

Pig (Porcine) Angiotensin II Receptor, Type 1 (AGTR1) interaction partners

Luminal ANG II is internalized as a complex with AT1R/AT2R heterodimers to target endoplasmic reticulum in LLC-PK1 cells, where it might trigger intracellular calcium responses.
AT1 and AT2 (show AGTR2 Proteins) receptors heterodimerize and are involved in the angiotensin II effect on SERCA (show ATP2A3 Proteins) in proximal kidney tubules.
A critical role for lipid raft microdomains in AGTR1-mediated signal transduction in neonatal glomerular mesengial cells.
AT1 receptors are positively coupled to the proliferative response of vascular smooth muscle cells to angiotensin II.

Angiotensin II Type-1 Receptor (AGTR1) Protein Profile

Protein Summary

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed\; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.

Alternative names and synonyms associated with Angiotensin II Type-1 Receptor (AGTR1)

angiotensin II receptor type 1 (AGTR1)
angiotensin II receptor, type 1a (Agtr1a)
angiotensin II receptor, type 1b (Agtr1b)
angiotensin II receptor type 1 S homeolog (agtr1.S)
angiotensin II receptor type 1 (Agtr1)
uncharacterized AGTR1 (AGTR1)
angiotensin II receptor type 1 L homeolog (agtr1.L)

1810074K20Rik protein
AG2S protein
Agtr-1a protein
agtr1 protein
agtr1-a protein
agtr1-b protein
agtr1.2 protein
AGTR1A protein
AGTR1B protein
AI551199 protein
Angtr-1a protein
at1 protein
AT1-R protein
AT1a protein
AT1AR protein
AT1B protein
AT1BR protein
AT1R protein
AT2R1 protein
AT2R1A protein
AT2R1B protein
AT3 protein
AT₁R protein
HAT1R protein
xAT protein
XAT-1 protein

Protein level used designations for AGTR1

, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , type-1 angiotensin II receptor type-1B angiotensin II receptor angiotensin II type-1A receptor angiotensin receptor 1 angiotensin receptor 1a type-1A angiotensin II receptor Angiotensin II receptor, type 1 (AT1B) angiotensin II receptor, type-1 angiotensin II type-1 receptor angiotensin II type-1B receptor angiotensin receptor 1b AT1 angiotensin II receptor 1 AT1-2 angiotensin 2 receptor, type 1, gene 2 angiotensin 2 receptor, type 1-B angiotensin II receptor, type 1 angiotensin II receptor, type 1-B angiotensin II type-1 receptor 2 angiotensin type 1 receptor type-1 angiotensin II receptor B type-1-like angiotensin II receptor 2 angiotensin II type 1 receptor AT1 ANG II receptor AT1 angiotensin II receptor Type-1 angiotensin II receptor angiotensin receptor Angiotensin II type-1 receptor AT1-1 Angiotensin 2 receptor, type 1-A Angiotensin II receptor, type 1-A Type-1-like angiotensin II receptor 1 angiotensin 2 receptor, type 1 L homeolog angiotensin 2 receptor, type 1-A angiotensin II receptor, type 1-A angiotensin II type-1 receptor 1 angiotensin type 1 type-1 angiotensin II receptor A

GENE ID	SPECIES
185	Homo sapiens
11607	Mus musculus
81638	Rattus norvegicus
281607	Bos taurus
378523	Xenopus laevis
396065	Gallus gallus
443107	Ovis aries
460762	Pan troglodytes
100009164	Oryctolagus cuniculus
100192325	Cavia porcellus
403836	Canis lupus familiaris
100303701	Meleagris gallopavo
100471220	Ailuropoda melanoleuca
100519976	Sus scrofa
398763	Xenopus laevis

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