Browse our anti-CD25 (IL2RA) Antibodies

Full name:: anti-Interleukin 2 Receptor, alpha Antibodies (IL2RA)

On www.antibodies-online.com are 1170 Interleukin 2 Receptor, alpha (IL2RA) Antibodies from 34 different suppliers available. Additionally we are shipping CD25 Kits (94) and CD25 Proteins (66) and many more products for this protein. A total of 1341 CD25 products are currently listed.

Synonyms:: CD25, IDDM10, IL-2RA, Il2r, IL2RAC, Ly-43, TCGFR

list all antibodies	Gene Name	GeneID	UniProt
	IL2RA	3559	P01589
	IL2RA	25704	P26897
	IL2RA	16184	P01590
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Most Popular Reactivities for anti-CD25 (IL2RA) Antibodies

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anti-Human CD25 Antibodies:

anti-Rat (Rattus) CD25 Antibodies:

anti-Mouse (Murine) CD25 Antibodies:

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Relevant Pathways for anti-CD25 Antibodies

Activated T Cell Proliferation

More product categories related to CD25 Antibody

Top referenced anti-CD25 Antibodies

Human Monoclonal CD25 Primary Antibody for FACS - ABIN1383666 : Heyll, Aul, Söhngen, Meckenstock, Arning, Wurm, Schmitt, Schneider: [Therapy of multiple myeloma by allogeneic bone marrow transplantation]. in Deutsche medizinische Wochenschrift (1946) 1991 (PubMed)
Show all 18 Pubmed References
Mouse (Murine) Monoclonal CD25 Primary Antibody for CyTox, IHC (fro) - ABIN2689117 : Lorenzo, Jaulin, Vita, Froussard, Ferrara, Jankovic, Theze: Structure-function study of the p55 subunit of murine IL-2 receptor by epitope mapping. in Journal of immunology (Baltimore, Md. : 1950) 1991 (PubMed)
Show all 15 Pubmed References
Mouse (Murine) Monoclonal CD25 Primary Antibody for FACS - ABIN2689124 : Chen, Ma, Young, Alt: IL-2 receptor alpha chain expression during early B lymphocyte differentiation. in International immunology 1995 (PubMed)
Show all 14 Pubmed References
Mouse (Murine) Monoclonal CD25 Primary Antibody for BR, FACS - ABIN1176951 : Ceredig, Lowenthal, Nabholz, MacDonald: Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells. in Nature 1985 (PubMed)
Show all 13 Pubmed References
Mouse (Murine) Monoclonal CD25 Primary Antibody for BR, FACS - ABIN2689118 : Crowley, Inaba, Witmer-Pack, Steinman: The cell surface of mouse dendritic cells: FACS analyses of dendritic cells from different tissues including thymus. in Cellular immunology 1989 (PubMed)
Show all 13 Pubmed References
Mouse (Murine) Monoclonal CD25 Primary Antibody for FACS, Func - ABIN1302515 : Yu, Feng, Shih, Lai: Increased p300 expression inhibits glucocorticoid receptor-T-cell receptor antagonism but does not affect thymocyte positive selection. in Molecular and cellular biology 2002 (PubMed)
Show all 8 Pubmed References
Mouse (Murine) Monoclonal CD25 Primary Antibody for FACS, Func - ABIN1302926 : Tenorio, Olguín, Fernández, Vieyra, Saavedra: Reduction of Foxp3+ cells by depletion with the PC61 mAb induces mortality in resistant BALB/c mice infected with Toxoplasma gondii. in Journal of biomedicine & biotechnology 2009 (PubMed)
Show all 8 Pubmed References
Mouse (Murine) Monoclonal CD25 Primary Antibody for FACS, Func - ABIN1302633 : Wei, Chuang, Li, Wei, Sun, Moritoki, Gershwin, Lian, Tian: CD4+ CD25+ Foxp3+ regulatory T cells protect against T cell-mediated fulminant hepatitis in a TGF-beta-dependent manner in mice. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
Show all 8 Pubmed References
Mouse (Murine) Monoclonal CD25 Primary Antibody for FACS, Func - ABIN1303127 : Aiba, Hirayama, Ogawa: Clonal proliferation and cytokine requirement of murine progenitors for natural killer cells. in Blood 1997 (PubMed)
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Mouse (Murine) Monoclonal CD25 Primary Antibody for FACS, Func - ABIN1302435 : Kish, Gorbachev, Fairchild: CD8+ T cells produce IL-2, which is required for CD(4+)CD25+ T cell regulation of effector CD8+ T cell development for contact hypersensitivity responses. in Journal of leukocyte biology 2005 (PubMed)
Show all 6 Pubmed References

More Antibodies against CD25 Interaction Partners

Human Interleukin 2 Receptor, alpha (IL2RA) interaction partners

The gene polymorphisms at the loci of IL2RA rs2104286 and rs12722489 are closely associated with susceptibility to MS in the Chinese.
Higher frequency of IL2RA SNP could not be detected among multiple sclerosis patients. The difference of frequencies was statistically insignificant between groups, probably, due to low power of analysis and inadequate sample size.
sIL (show PMEL Antibodies)-2R could be a promising new marker for determining inflammatory disease activity in CRPS.
Relationship between soluble CD25 and gene expression in healthy individuals and patients with multiple sclerosis.
Increased serum level of soluble interleukin-2 (show IL2 Antibodies) receptor is associated with a worse response of metastatic clear cell renal cell carcinoma (show MOK Antibodies) to interferon alpha and sequential VEGF (show VEGFA Antibodies)-targeting therapy.
Data show that interleukin-2 receptor alpha, tumor necrosis factor receptor 1 (show TNFRSF1A Antibodies), serum STimulation-2 (IL1RL1 (show IL1RL1 Antibodies) gene product), and regenerating islet-derived 3-alpha (show REG3A Antibodies) were significantly associated with non-relapse mortality.
Our results show that the frequency of Tregs is altered in a large cohort of long-term T1D patients, a profound decrease in CD25 expression and altered IL-2 (show IL2 Antibodies) signaling are typical features of Tregs populations in long-term diabetic patients and their relatives.
High IL2RA expression is associated with CRLF2 (show CRLF2 Antibodies)-rearranged acute lymphoblastic leukemia.
Inhibits CD25 translation through regulation of the LKB1 (show STK11 Antibodies)-AMPK (show PRKAA1 Antibodies)-mTOR (show FRAP1 Antibodies) pathway to suppress T cells.
Among patients with a low pretreatment sIL (show PMEL Antibodies)-2R level who exhibited a positive response to R-CHOP (show DDIT3 Antibodies), the posttreatment sIL (show PMEL Antibodies)-2R level may help to identify those with a poor prognosis.

Mouse (Murine) Interleukin 2 Receptor, alpha (IL2RA) interaction partners

Each mutation decreased STAT5 (show STAT5A Antibodies) binding and altered IL-2 (show IL2 Antibodies)-induced Il2ra gene expression, revealing that individual elements within the superenhancer were not functionally redundant and that all were required for normal gene expression.
Analyze the percentage of CD4 (show CD4 Antibodies)(+)CD25(-)T cells.
Data indicate that there was a differential transcription of 381 genes which changed greater than two fold in B1a of p40-/-IL-2Ralpha-/- mice.
At single cell level, IL-2 (show IL2 Antibodies) is binary (digital) and CD25 is graded expressed, whereas at population level both parameters show graded expression correlating with the antigen amount.
Results indicate that conjugated-interleukin-2 (IL2 (show IL2 Antibodies)) protein derived from NKTR (show NKTR Antibodies)-214 occupy interleukin-2 (IL2 (show IL2 Antibodies)) receptor complex (IL2Ralphabetagamma) to a greater extent compared to free-IL2 (show IL2 Antibodies) protein.
CDK6 (show CDK6 Antibodies)-mediated suppression of CD25 is required for initiation of T-ALL by activated Notch1 (show NOTCH1 Antibodies). . Pharmacologic inhibition of CDK6 (show CDK6 Antibodies) kinase induces CD25 and RUNX1 (show RUNX1 Antibodies) expression, cell cycle arrest and apoptosis in mouse and human T-ALL.
Combination with anti-programmed cell death protein-1 (PD-1 (show PDCD1 Antibodies)) antibodies promoted complete tumor rejection, indicating the relevance of CD25 antigen as a therapeutic target and promising substrate for future combination approaches in immune-oncology.
Intratesticular inoculation with donor antigens promotes long-term skin allograft survival induced by conventional costimulatory blockade via the induction of both CD8 (show CD8A Antibodies) + CD122 (show IL2RB Antibodies)+ and CD4 (show CD4 Antibodies) + CD25+ Treg cells.
glucosamine interferes with N-glycosylation of CD25, and thereby attenuates IL-2 (show IL2 Antibodies) downstream signaling
Expansion of CD25-expressing innate lymhpoid cells by IL-2 (show IL2 Antibodies)/anti-IL-2 (show IL2 Antibodies) complexes leads to a reduction in very low-density lipoprotein cholesterol and atherosclerosis.

Pig (Porcine) Interleukin 2 Receptor, alpha (IL2RA) interaction partners

IL2 (show IL2 Antibodies)-R was equally expressed in interfollicular tissue and in follicles, whereas in moderate and severe cases of postweaning multisystemic wasting syndrome, it was detected in interfollicular remnants only
The appearance of CD25 after activation of porcine dendritic cells, is reported.

Cow (Bovine) Interleukin 2 Receptor, alpha (IL2RA) interaction partners

Differential expression of CD25 and IDO (show IDO1 Antibodies) mRNA with high and low virulence bovine viral diarrhea virus might reflect temporal differences in transcription during the immune response elicited by these viral strains.
Increase of CD25 expression on bovine neutrophils correlates with mastitis severity in post-partum and early lactating dairy cows.
The PGE2-mediated down-regulation of CD25 expression on T cells is mediated via the EP4 (show PTGER4 Antibodies) receptor, although selective activation of the EP2 receptor up-regulates the CD25 expression on these cells.
There is a positive correlation between the intensity of CD25 expression and the expression of the transcription Foxp3 (show FOXP3 Antibodies) factor in bovine CD8 (show CD8A Antibodies)(+) cells.
determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25, CD44 (show CD44 Antibodies), and CD62L (show SELL Antibodies) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.
Pretreatment of neonatal PBMC with IL-1beta (show IL1B Antibodies), TNF-alpha (show TNF Antibodies) or IFN-gamma (show IFNG Antibodies) promotes mitogenic response to ConA through up-regulating the production of IL-2 (show IL2 Antibodies) and the expression of the mature IL-2 (show IL2 Antibodies) receptor.
These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 Antibodies)(+)CD25(high) T cell population, which showed Foxp3 (show FOXP3 Antibodies) transcription/expression, natural regulatory activity did not reside in this cell population

CD25 (IL2RA) Antigen Profile

Antigen Summary

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Alternative names and synonyms associated with CD25 (IL2RA)

interleukin 2 receptor subunit alpha (IL2RA) antibody
interleukin 2 receptor subunit alpha (Il2ra) antibody
interleukin-2 receptor subunit alpha-like (LOC100222957) antibody
interleukin 2 receptor, alpha chain (Il2ra) antibody

CD25 antibody
IDDM10 antibody
IL-2RA antibody
Il2r antibody
IL2RAC antibody
Ly-43 antibody
TCGFR antibody

Protein level used designations for IL2RA

, , , , , , , , , , , , , , , , , , , , , IL-2 receptor subunit alpha IL-2-RA IL-2R subunit alpha IL2-RA TAC antigen interleukin-2 receptor subunit alpha p55 IL-2 receptor alpha subunit interleukin 2 receptor, alpha chain interleukin-2 receptor alpha chain IL-2 alpha receptor IL2 receptor alpha interleukin-2 alpha receptor interleukin 2 receptor alpha chain interleukin-2 receptor alpha subunit IL-2 Receptor alpha chain interleukin 2 receptor, alpha IL-2R alpha chain p55 chain IL-2R alpha cytokine receptor CD25 antigen

GENE ID	SPECIES
3559	Homo sapiens
25704	Rattus norvegicus
395294	Gallus gallus
403870	Canis lupus familiaris
443435	Ovis aries
450884	Pan troglodytes
574300	Macaca mulatta
100222957	Taeniopygia guttata
16184	Mus musculus
396814	Sus scrofa
281861	Bos taurus
100715332	Cavia porcellus
493953	Felis catus
102123605	Macaca fascicularis

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Show all anti-Interleukin 2 Receptor, alpha (IL2RA) Antibodies with Pubmed References