Browse our anti-CD25 (IL2RA) Antibodies

Human Interleukin 2 Receptor, alpha (IL2RA) interaction partners

1. sIL (show PMEL Antibodies)-2R could be a promising new marker for determining inflammatory disease activity in CRPS.

2. Relationship between soluble CD25 and gene expression in healthy individuals and patients with multiple sclerosis.

3. Increased serum level of soluble interleukin-2 (show IL2 Antibodies) receptor is associated with a worse response of metastatic clear cell renal cell carcinoma (show MOK Antibodies) to interferon alpha (show IFNA Antibodies) and sequential VEGF (show VEGFA Antibodies)-targeting therapy.

4. Data show that interleukin-2 receptor alpha, tumor necrosis factor receptor 1 (show TNFRSF1A Antibodies), serum STimulation-2 (IL1RL1 (show IL1RL1 Antibodies) gene product), and regenerating islet-derived 3-alpha (show REG3A Antibodies) were significantly associated with non-relapse mortality.

5. Our results show that the frequency of Tregs is altered in a large cohort of long-term T1D patients, a profound decrease in CD25 expression and altered IL-2 (show IL2 Antibodies) signaling are typical features of Tregs populations in long-term diabetic patients and their relatives.

6. High IL2RA expression is associated with CRLF2 (show CRLF2 Antibodies)-rearranged acute lymphoblastic leukemia.

7. Inhibits CD25 translation through regulation of the LKB1 (show STK11 Antibodies)-AMPK (show PRKAA1 Antibodies)-mTOR (show FRAP1 Antibodies) pathway to suppress T cells.

8. Among patients with a low pretreatment sIL (show PMEL Antibodies)-2R level who exhibited a positive response to R-CHOP (show DDIT3 Antibodies), the posttreatment sIL (show PMEL Antibodies)-2R level may help to identify those with a poor prognosis.

9. The findings not only confirm the predictive power of CD25 expression for Philadelphia chromosome translocation (Ph)+ but also demonstrate that CD25 expression is associated with RD (a biomarker correlated with prognosis) in Ph- patients. The latter finding is likely associated with underlying molecular abnormalities, including Ph-like genotype.

10. Through GWAS, we found that emotion dysregulation is associated at genome-wide level significance in a sex-specific manner, with a SNP in IL2RA in men.

Mouse (Murine) Interleukin 2 Receptor, alpha (IL2RA) interaction partners

1. Each mutation decreased STAT5 (show STAT5A Antibodies) binding and altered IL-2 (show IL2 Antibodies)-induced Il2ra gene expression, revealing that individual elements within the superenhancer were not functionally redundant and that all were required for normal gene expression.

2. Analyze the percentage of CD4 (show CD4 Antibodies)(+)CD25(-)T cells.

3. Data indicate that there was a differential transcription of 381 genes which changed greater than two fold in B1a of p40-/-IL-2Ralpha-/- mice.

4. At single cell level, IL-2 (show IL2 Antibodies) is binary (digital) and CD25 is graded expressed, whereas at population level both parameters show graded expression correlating with the antigen amount.

5. Results indicate that conjugated-interleukin-2 (IL2 (show IL2 Antibodies)) protein derived from NKTR (show NKTR Antibodies)-214 occupy interleukin-2 (IL2 (show IL2 Antibodies)) receptor complex (IL2Ralphabetagamma) to a greater extent compared to free-IL2 (show IL2 Antibodies) protein.

6. CDK6 (show CDK6 Antibodies)-mediated suppression of CD25 is required for initiation of T-ALL by activated Notch1 (show NOTCH1 Antibodies). . Pharmacologic inhibition of CDK6 (show CDK6 Antibodies) kinase induces CD25 and RUNX1 (show RUNX1 Antibodies) expression, cell cycle arrest and apoptosis in mouse and human T-ALL.

7. Combination with anti-programmed cell death protein-1 (PD-1 (show PDCD1 Antibodies)) antibodies promoted complete tumor rejection, indicating the relevance of CD25 antigen as a therapeutic target and promising substrate for future combination approaches in immune-oncology.

8. Intratesticular inoculation with donor antigens promotes long-term skin allograft survival induced by conventional costimulatory blockade via the induction of both CD8 (show CD8A Antibodies) + CD122 (show IL2RB Antibodies)+ and CD4 (show CD4 Antibodies) + CD25+ Treg cells.

9. glucosamine interferes with N-glycosylation of CD25, and thereby attenuates IL-2 (show IL2 Antibodies) downstream signaling

10. Expansion of CD25-expressing innate lymhpoid cells by IL-2 (show IL2 Antibodies)/anti-IL-2 (show IL2 Antibodies) complexes leads to a reduction in very low-density lipoprotein cholesterol and atherosclerosis.

Pig (Porcine) Interleukin 2 Receptor, alpha (IL2RA) interaction partners

1. IL2 (show IL2 Antibodies)-R was equally expressed in interfollicular tissue and in follicles, whereas in moderate and severe cases of postweaning multisystemic wasting syndrome, it was detected in interfollicular remnants only

2. The appearance of CD25 after activation of porcine dendritic cells, is reported.

Cow (Bovine) Interleukin 2 Receptor, alpha (IL2RA) interaction partners

1. Differential expression of CD25 and IDO (show IDO1 Antibodies) mRNA with high and low virulence bovine viral diarrhea virus might reflect temporal differences in transcription during the immune response elicited by these viral strains.

2. Increase of CD25 expression on bovine neutrophils correlates with mastitis severity in post-partum and early lactating dairy cows.

3. The PGE2-mediated down-regulation of CD25 expression on T cells is mediated via the EP4 (show PTGER4 Antibodies) receptor, although selective activation of the EP2 receptor up-regulates the CD25 expression on these cells.

4. There is a positive correlation between the intensity of CD25 expression and the expression of the transcription Foxp3 (show FOXP3 Antibodies) factor in bovine CD8 (show CD8A Antibodies)(+) cells.

5. determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25, CD44 (show CD44 Antibodies), and CD62L (show SELL Antibodies) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.

6. Pretreatment of neonatal PBMC with IL-1beta (show IL1B Antibodies), TNF-alpha (show TNF Antibodies) or IFN-gamma (show IFNG Antibodies) promotes mitogenic response to ConA through up-regulating the production of IL-2 (show IL2 Antibodies) and the expression of the mature IL-2 (show IL2 Antibodies) receptor.

7. These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 Antibodies)(+)CD25(high) T cell population, which showed Foxp3 (show FOXP3 Antibodies) transcription/expression, natural regulatory activity did not reside in this cell population