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|Antigen||Interferon, alpha 1 (IFNA1) Antibodies|
|Conjugate||This IFNA1 antibody is un-conjugated Alternatives|
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
Product Details anti-IFNA1 AntibodyTarget Details IFNA1 Application Details Handling Images
|Purification||Purified by Protein A/G|
|Immunogen||Purified recombinant human IFN-alpha1|
|Plasmids, Primers & others|
Target Details IFNA1Product Details anti-IFNA1 Antibody Application Details Handling Images back to top
|Alternative Name||IFNA1 (IFNA1 Antibody Abstract)|
|Background||This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.|
|Pathways||JAK-STAT Signaling, Hepatitis C|
Application DetailsProduct Details anti-IFNA1 Antibody Target Details IFNA1 Handling Images back to top
Positive Control: Stimulated human peripheral blood mononuclear cells.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Western Blot (1-2 μg/mL), Immunohistochemistry (frozen), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IFNA1 Antibody Target Details IFNA1 Application Details Images back to top
|Buffer||10 mM PBS with 0.05 % BSA & 0.05 % azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C,-80 °C|
|Storage Comment||Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.|
|Expiry Date||24 months|