IFNA1 antibody (AA 150-189)

Catalog No. ABIN1715112

Product Details anti-IFNA1 Antibody

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Binding Specificity: AA 150-189

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: The antibody targets Mouse IFNA1 protein, but will cross-react with IFNA11 and IFNA16

Cross-Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse IFNA1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Alternative Name: IFNA1 (IFNA1 Products)

Synonyms: IFL antibody, IFN antibody, IFN-ALPHA antibody, IFN-alphaD antibody, IFNA13 antibody, IFNA@ antibody, Ifa1 antibody, IFN-ALPHA-1 antibody, IFN1@ antibody, IFNA1 antibody, IFN-alpha antibody, IFN-gamma antibody, IFNA antibody, IFNA2 antibody, IFNA6 antibody, IFN-alpha1 antibody, interferon alpha 13 antibody, interferon alpha 1 antibody, interferon, alpha 1 antibody, interferon, alpha 13 antibody, interferon antibody, interferon-alpha 1 antibody, interferon, alpha, leukocyte antibody, interferon-alpha-14 antibody, IFNA13 antibody, IFNA1 antibody, Ifna1 antibody, ifna1 antibody, IFNA3 antibody, IFN-ALPHA-14 antibody

Background:

Synonyms: IFN alpha, IFN-alpha-1, IFA1, Interferon alpha 1, IFNA1_MOUSE, IFNA11, IFNAB_MOUSE, IFN-alpha-11, Interferon alpha-11, Limitin, Q810G1_MOUSE, IFNA16, IFNA6T

Background: IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages, they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes, and they also increase the ability of uninfected host cells to resist new infection by virus. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes. IFNA1 is produced by macrophages and has antiviral activities.

Gene ID: 15962

UniProt: P01572

Pathways: JAK-STAT Signaling, Hepatitis C