IFNA1 antibody
Quick Overview for IFNA1 antibody (ABIN7251595)
Target
See all IFNA1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Synthetic peptide of human IFNA1/IFNA13
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Isotype
- IgG
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Application Notes
- IHC 1:30-1:150, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.96 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- IFNA1 (Interferon, alpha 1 (IFNA1))
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Alternative Name
- IFNA1/IFNA13
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Background
- IFNA1 (interferon-alpha) is a member of the Type I IFN (1) family best known for their antiviral activity. It is a key cytokine regulating the activity of B cells,T-helper cells (Th cells),cDCs and natural killer cells (NK cells). Interferon-alpha induces B cell maturation into plasma cells and immunoglobulin production. Interferon-alpha plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). Interferon-alpha was the first cytokine to show clinical benefit in the treatment of certain types of cancer,including melanoma,chronic myelogenous leukemia,and renal cancer.
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UniProt
- P01562
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Pathways
- JAK-STAT Signaling, Hepatitis C
Target
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