Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SensoLyte® 440 Cathepsin B Assay Kit

FRET Fluorometric
Catalog No. ABIN1882437

Quick Overview for SensoLyte® 440 Cathepsin B Assay Kit (ABIN1882437)

Target

See all Cathepsin B (CTSB) Kits
Cathepsin B (CTSB)

Detection Method

Fluorometric

Application

Fluorescence Resonance Energy Transfer Microscopy (FRET)
  • Brand

    SensoLyte®

    Characteristics

    The SensoLyte® 440 Cathepsin B Assay Kit provides a fluorogenic peptide for measurement of enzyme activity. This peptide releases the AMC (7-amino-4-methylcoumarin) fluorophore upon cathepsin B cleavage and can be detected with excitation at 354 nm and emission at 442 nm.
  • Comment

    FRET-based Assay Kit

    Restrictions

    For Research Use only
  • Handling Advice

    Protect Components A and B from light and moisture.

    Storage

    -80 °C

    Storage Comment

    Store all kit components at -20 °C, except for Component C. Store Component C at -80 °C. Component D can be stored at room temperature for convenience
  • Vidal, Aguiar, Phansalkar, McAlpine, Napolitano, Chen, Araújo, Pauli, Bedran-Russo: "Galloyl moieties enhance the dentin biomodification potential of plant-derived catechins." in: Acta biomaterialia, Vol. 10, Issue 7, pp. 3288-94, (2014) (PubMed).

  • Target

    Cathepsin B (CTSB)

    Alternative Name

    Cathepsin B

    Background

    Cathepsins are a class of globular lysosomal proteases playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. The cathepsin family consists of 12 cysteine proteases with broad exo- and endopeptidase activity, of which Cathepsin B is a member. Elevated levels of cathepsin B were detected in metastases and neurological disorders including Alzheimer's disease (AD).
You are here:
Chat with us!