Quick Overview for SensoLyte® 440 Cathepsin B Assay Kit (ABIN1882437)
Target
See all Cathepsin B (CTSB) KitsDetection Method
Application
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Brand
- SensoLyte®
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Characteristics
- The SensoLyte® 440 Cathepsin B Assay Kit provides a fluorogenic peptide for measurement of enzyme activity. This peptide releases the AMC (7-amino-4-methylcoumarin) fluorophore upon cathepsin B cleavage and can be detected with excitation at 354 nm and emission at 442 nm.
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Comment
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FRET-based Assay Kit
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Restrictions
- For Research Use only
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Handling Advice
- Protect Components A and B from light and moisture.
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Storage
- -80 °C
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Storage Comment
- Store all kit components at -20 °C, except for Component C. Store Component C at -80 °C. Component D can be stored at room temperature for convenience
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: "Galloyl moieties enhance the dentin biomodification potential of plant-derived catechins." in: Acta biomaterialia, Vol. 10, Issue 7, pp. 3288-94, (2014) (PubMed).
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: "Galloyl moieties enhance the dentin biomodification potential of plant-derived catechins." in: Acta biomaterialia, Vol. 10, Issue 7, pp. 3288-94, (2014) (PubMed).
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- Cathepsin B (CTSB)
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Alternative Name
- Cathepsin B
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Background
- Cathepsins are a class of globular lysosomal proteases playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. The cathepsin family consists of 12 cysteine proteases with broad exo- and endopeptidase activity, of which Cathepsin B is a member. Elevated levels of cathepsin B were detected in metastases and neurological disorders including Alzheimer's disease (AD).
Target
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