Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

IL1A ELISA Kit

This Human IL1A ELISA Kit is a Colorimetric ELISA Kit designed to quantify Human IL1A.
Catalog No. ABIN2042511

Quick Overview for IL1A ELISA Kit (ABIN2042511)

Target

See all IL1A ELISA Kits
IL1A (Interleukin 1 alpha (IL1A))

Reactivity

  • 14
  • 13
  • 11
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Detection Method

Colorimetric

Method Type

Sandwich ELISA

Detection Range

4.7-300 pg/mL

Application

ELISA
  • Minimum Detection Limit

    4.7 pg/mL

    Cross-Reactivity (Details)

    There is no detectable cross-reactivity with other relevant proteins.

    Sensitivity

    < 0.5 pg/mL

    Components

    96-well plate pre-coated with anti-IL-1 alpha, Human
    Lyophilized recombinant IL-1 alpha, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • Plate

    Pre-coated

    Protocol

    Sandwich ELISA quantitative detection kit for Human IL-1 alpha in cell culture supernates, serum and plasma (heparin, EDTA, citrate.Interleukin-1 alpha (IL-1 alpha) and interleukin-1 beta (IL-1 beta) are two biochemically distinct, but distantly related, polypeptidic cytokines that play a key role in inflammation, immunologic reactions, and tissue repair.1 IL-1 alpha has been implicated in the pathogenesis of infectious, autoimmune and inflammatory diseases.2 Recently, it has been shown that IL-1 alpha is identical to hematopoietin 1, which is described as a hematopoietic growth factor acting on early progenitor cells in synergy with other hematopoietic growth factors.1 The human interleukin 1 alpha gene is assigned to chromosome 2.3 Genetic polymorphisms at interleukin (IL)-1alpha and IL-1beta have been recently suggested to be associated with severity of adult periodontitis.4 The murine IL-1 alpha and IL-1 beta genes encode structurally and evolutionarily related cytokines that exert a regulatory role in numerous physiological processes including hemopoiesis.5 The standard product used in this kit is recombinant human IL-1 with the molecular mass of 18kD.

    Restrictions

    For Research Use only
  • Storage

    4 °C/-20 °C
  • Target See all IL1A ELISA Kits

    IL1A (Interleukin 1 alpha (IL1A))

    Alternative Name

    IL-1 alpha

    Gene ID

    3552

    UniProt

    P01583

    Pathways

    NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
You are here:
Chat with us!