P-Selectin ELISA Kit

Catalog No. ABIN2648542

Human P-Selectin ELISA Kit Colorimetric assay for quantification of Human P-Selectin.

Quick Overview for P-Selectin ELISA Kit (ABIN2648542)

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reactivity: Human

Detection Method: Colorimetric

Application: ELISA

Product Details P-Selectin ELISA Kit

Characteristics: A soluble form of P-selectin, which might represent a proteolytic fragment or a soluble splice variant lacking the transmembrane domain, is found in serum and plasma (2). High expression of P-selectin or sP-selectin has been implicated in several inflammatory disorders, including adult respiratory distress syndrome, acute lung injury, ischemia-reperfusion injury, Gram-negative septic shock, thrombotic diseases, malaria, systemic sclerosis, connective tissue disease and rheumatoid arthritis. Furthermore, lung injury scores correlate significantly with sP-selectin in plasma of patients with acute lung injury (3) and (4).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Plate: Pre-coated

Protocol: The CD62P Kit is a solid phase sandwich Enzyme Linked-Immuno-Sorbent Assay (ELISA). A monoclonal antibody specific for CD62P has been coated onto the wells of the microtiter strips provided. Samples, including standards of known CD62P concentrations and unknowns are pipetted into these wells.

Restrictions: For Research Use only

Handling

Storage: 4 °C

Target Details for P-Selectin

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Alternative Name: CD62P / P-Selectin