NAMPT ELISA Kit

Catalog No. ABIN2745468

This Colorimetric ELISA kit is designed for the quantitative measurement of Human NAMPT.

Quick Overview for NAMPT ELISA Kit (ABIN2745468)

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 0.125-8 ng/mL

Application: ELISA

Sample Type: Serum

Product Details NAMPT ELISA Kit

Minimum Detection Limit: 0.125 ng/mL

Analytical Method: Quantitative

Specificity: Detects human Nampt.

Cross-Reactivity: Human

Cross-Reactivity (Details): Weakly cross-reacts (<15 %) with mouse Nampt and rat Nampt. Does not cross-react with human adiponectin, human resistin, human vaspin or human RBP4. Has been shown to specifically detect the physiologically relevant Nampt dimer in human serum samples.

Sensitivity: 30 pg/mL

Characteristics: Nampt (Visfatin/PBEF) (human) ELISA Kit

Application Details

Application Notes: Note: Does not work with plasma samples.

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: +4°C
12 months after the day of manufacturing. See expiry date on ELISA Kit box.

Target Details for NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Alternative Name: Nampt

Background: Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDA adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. It has been shown that Nampt expression is increased in different diseases, like diabetes, obesity, fetal growth retardation, sepsis, inflammatory bowel disease, Crohn's disease and rheumatoid arthritis. Furthermore, Nampt might be a marker of pre-eclampsia and of endothelial health.

UniProt: P43490