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Thymic Stromal Lymphopoietin ELISA Kit

Human Thymic Stromal Lymphopoietin ELISA Kit Colorimetric assay for quantification of Human Thymic Stromal Lymphopoietin.
Catalog No. ABIN4987141
$548.90
Plus shipping costs $50.00
96 tests
Shipping to: United States
Delivery in 6 to 8 Business Days

Quick Overview for Thymic Stromal Lymphopoietin ELISA Kit (ABIN4987141)

Target

See all Thymic Stromal Lymphopoietin (TSLP) ELISA Kits
Thymic Stromal Lymphopoietin (TSLP)

Reactivity

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Human

Detection Method

Colorimetric

Method Type

Sandwich ELISA

Detection Range

3.9-250 pg/mL

Application

ELISA

Sample Type

Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
  • Minimum Detection Limit

    3.9 pg/mL

    Analytical Method

    Quantitative

    Specificity

    Natural and recombinant Human TSLP Ligand

    Sensitivity

    2 pg/mL

    Material not included

    • Microplate reader.
    • Pipettes and pipette tips.
    • EP tube Deionized or distilled water.
  • Application Notes

    Detection Wavelength: 450 nm

    Sample Volume

    20 μL

    Assay Time

    3 h

    Plate

    Pre-coated

    Restrictions

    For Research Use only
  • Storage

    4 °C
  • Target See all Thymic Stromal Lymphopoietin (TSLP) ELISA Kits

    Thymic Stromal Lymphopoietin (TSLP)

    Alternative Name

    TSLP

    Background

    Thymic Stromal Lymphopoietin (TSLP) is a 23 kDa member of the IL-7 family of a-helical cytokines (1-3). It is a monomeric glycoprotein that is synthesized as a 159 amino acid (aa) precursor (4, 5). TSLP appears to have species-specific functions. In mouse, TSLP was initially reported to act on NK cells, mast cells, and B cells, but this does not appear to occur in humans. In humans, TSLP is produced by a number of divergent cell types, all of which appear to target T cells, monocytes, and/or dendritic cells (2). On TCR-activated T cells, TSLP directly induces T cell proliferation (6). The significance of this direct action is unclear. On monocytes, TSLP is reported to induce the release of multiple chemokines that target CCR4, a receptor associated with the Th2 subset (5). TSLP is best known for its direct action on subsets of dendritic cells. In thymic medulla, Hassell
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