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Thymic Stromal Lymphopoietin ELISA Kit

Human Thymic Stromal Lymphopoietin ELISA Kit Colorimetric assay for quantification of Human Thymic Stromal Lymphopoietin.
Catalog No. ABIN4987141

Quick Overview for Thymic Stromal Lymphopoietin ELISA Kit (ABIN4987141)

Target

See all Thymic Stromal Lymphopoietin (TSLP) ELISA Kits
Thymic Stromal Lymphopoietin (TSLP)

Reactivity

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Human

Detection Method

Colorimetric

Method Type

Sandwich ELISA

Detection Range

3.9-250 pg/mL

Application

ELISA

Sample Type

Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
  • Minimum Detection Limit

    3.9 pg/mL

    Analytical Method

    Quantitative

    Specificity

    Natural and recombinant Human TSLP Ligand

    Sensitivity

    2 pg/mL

    Material not included

    • Microplate reader.
    • Pipettes and pipette tips.
    • EP tube Deionized or distilled water.
  • Application Notes

    Detection Wavelength: 450 nm

    Sample Volume

    20 μL

    Assay Time

    3 h

    Plate

    Pre-coated

    Restrictions

    For Research Use only
  • Storage

    4 °C
  • Target See all Thymic Stromal Lymphopoietin (TSLP) ELISA Kits

    Thymic Stromal Lymphopoietin (TSLP)

    Alternative Name

    TSLP

    Background

    Thymic Stromal Lymphopoietin (TSLP) is a 23 kDa member of the IL-7 family of a-helical cytokines (1-3). It is a monomeric glycoprotein that is synthesized as a 159 amino acid (aa) precursor (4, 5). TSLP appears to have species-specific functions. In mouse, TSLP was initially reported to act on NK cells, mast cells, and B cells, but this does not appear to occur in humans. In humans, TSLP is produced by a number of divergent cell types, all of which appear to target T cells, monocytes, and/or dendritic cells (2). On TCR-activated T cells, TSLP directly induces T cell proliferation (6). The significance of this direct action is unclear. On monocytes, TSLP is reported to induce the release of multiple chemokines that target CCR4, a receptor associated with the Th2 subset (5). TSLP is best known for its direct action on subsets of dendritic cells. In thymic medulla, Hassell
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