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Hemopexin ELISA Kit

This Human Hemopexin ELISA Kit is a Colorimetric ELISA Kit designed to quantify Human Hemopexin.
Catalog No. ABIN5510645

Quick Overview for Hemopexin ELISA Kit (ABIN5510645)

Target

See all Hemopexin (HPX) ELISA Kits
Hemopexin (HPX)

Binding Specificity

AA 24-462

Reactivity

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Human

Detection Method

Colorimetric

Method Type

Sandwich ELISA

Application

ELISA
  • Purpose

    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Hemopexin

    Brand

    PicoKine™

    Analytical Method

    Quantitative

    Specificity

    Expression system for standard: NSO
    Immunogen sequence: T24-H462

    Cross-Reactivity (Details)

    There is no detectable cross-reactivity with other relevant proteins.

    Characteristics

    Tissue Specificity: Expressed by the liver and secreted in plasma.

  • Plate

    Pre-coated

    Restrictions

    For Research Use only
  • Storage

    4 °C,-20 °C

    Storage Comment

    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

    Expiry Date

    12 months
  • Target See all Hemopexin (HPX) ELISA Kits

    Hemopexin (HPX)

    Alternative Name

    HPX

    Background

    Protein Function: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

    Background: Hemopexin (or haemopexin, HPX), also known as beta-1B-glycoprotein, is a protein that in humans is encoded by the HPX gene and belongs to hemopexin family of proteins. Hemopexin binds heme with the highest affinity of any known protein. Its function is scavenging the heme released or lost by the turnover of heme proteins such as hemoglobin and thus protects the body from the oxidative damage that free heme can cause. In addition, hemopexin releases its bound ligand for internalisation upon interacting with a specific receptor situated on the surface of liver cells. This function of hemopexin is to preserve the body's iron.

    Synonyms: Hemopexin,Beta-1B-glycoprotein,HPX,

    Full Gene Name: Hemopexin

    Cellular Localisation: Secreted.

    UniProt

    P02790

    Pathways

    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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