PON1 ELISA Kit
Quick Overview for PON1 ELISA Kit (ABIN5510758)
Target
See all PON1 ELISA KitsBinding Specificity
Reactivity
Detection Method
Method Type
Application
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Purpose
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse PON1
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Brand
- PicoKine™
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Analytical Method
- Quantitative
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Specificity
- Expression system for standard: E.Coli, Immunogen sequence: A30-L355
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Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Characteristics
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Tissue Specificity: Plasma, liver, kidney, heart, brain, small intestine and lung. In the plasma, associated with HDL.
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Paraoxonase 1 (PON1) ELISA Kit
PON1 Reactivity: Mouse Colorimetric Sandwich ELISA 12.5 ng/mL - 800 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Paraoxonase 1 (PON1) ELISA KitPON1 Reactivity: Human Colorimetric Sandwich ELISA 3.12 ng/mL - 200 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Paraoxonase 1 (PON1) ELISA KitPON1 Reactivity: Rat Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Paraoxonase 1 (PON1) ELISA KitPON1 Reactivity: Human AA 2-355 Colorimetric Sandwich ELISA 31.2-2000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma (heparin), Serum, Tissue Homogenate
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Plate
- Pre-coated
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Restrictions
- For Research Use only
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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Expiry Date
- 12 months
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- PON1 (Paraoxonase 1 (PON1))
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Alternative Name
- Pon1
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Background
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Protein Function: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification.
Background: Serum paraoxonase/arylesterase 1 (PON1) also known as aromatic esterase 1 or serum aryldialkylphosphatase 1 is an enzyme that in humans is encoded by the PON1 gene. The PON gene was mapped to chromosome 7q21-q22, and the mouse Pon1 gene was mapped to the proximal end of chromosome 6. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL).
Synonyms: Serum paraoxonase/arylesterase 1, PON 1, 3.1.1.2
Full Gene Name: paraoxonase 1
Cellular Localisation: Secreted, extracellular space. -
UniProt
- P52430
Target See all PON1 ELISA Kits
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