Anti-SSB ELISA Kit
Reactivity: Human
Colorimetric
Sandwich ELISA
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- Target
- Anti-SSB
- Reactivity
- Human
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Application
- ELISA
- Analytical Method
- Quantitative
- Characteristics
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ELISA kit for the detection of SSB in the research laboratory
Alternative Names: SSB ELISA kit, La ELISA kit
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- Application Notes
- Optimal conditions to be determined by end-user
- Plate
- Pre-coated
- Assay Procedure
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AntiSSB is an indirect solid phase enzyme immunometric assay (ELISA). It is designed for the quantitative measurement of IgG class autoantibodies directed against the extractable nuclear antigens SSB (La). The microplate is coated with SSB (La). The microplate can be divided into 12 modules of 8 wells each or can be used completely for 96determinations. Each well can be separated from the module (
- Restrictions
- For Research Use only
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- Storage
- 4 °C
- Storage Comment
- Store at 2-8 °C.
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- Target
- Anti-SSB
- Target Type
- Antibody
- Background
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In patients with Sjögren-Syndrome antibodies against SSA and SSB often occur in combination. Due to the strong association of SSA and SSB antibodies to the HLADR3 and DR2 phenotypes a genetic predisposition is suspected. The anti-SSA protein passes the placenta and may cause the development of SLE in neonates. Immunoreactive proteins may occur in various combinations and bind also to 'host proteins' of viral origin. They induce synthesis of polyclonal autoantibodies, of the IgG, IgM and IgA class. Especially for mixed connective tissue diseases a relation to viral infections by EBV is indicated.
Synonyms: SSB ELISA kit, La ELISA kit.
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