Sphingosine 1 Phosphate Receptor 1 (EDG-1) Lysate
S1PR1
WB
Whole Cell Lysate
Overexpression Lysate
HEK 293T Cells
Catalog No. ABIN2764171
Quick Overview for Sphingosine 1 Phosphate Receptor 1 (EDG-1) Lysate (ABIN2764171)
Target
S1PR1
(Sphingosine-1-Phosphate Receptor 1 (S1PR1))
Application
Western Blotting (WB)
Lysed Cells
HEK 293T Cells
Lysate Type
Overexpression Lysate
Lysate Fraction
Whole Cell Lysate
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Characteristics
- EDG1 (S1P1) Transfected Cell Positive Control Lysate,EDG-1 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-1 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-1 is expressed in cardiovascular, leukocyte- containing and other tissues.
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Application Notes
- For use as a positive control with EDG1 (S1P1) polyclonal antibody (ABIN306730) for Western blot analysis.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Provided in 10 % glycerol, 0.063 M Tris-HCl ( pH 6.8), 2 % SDS and 0.002 % bromophenol blue, 5 % 2-mercaptoethanol
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Storage
- -20 °C
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Storage Comment
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
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Alternative Name
- Sphingosine 1 Phosphate Receptor 1 (EDG-1)
Target
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