Browse our anti-EIF2B4 (EIF2B4) Antibodies

Full name:: anti-Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa Antibodies (EIF2B4)

On www.antibodies-online.com are 69 Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa (EIF2B4) Antibodies from 20 different suppliers available. Additionally we are shipping EIF2B4 Proteins (4) and and many more products for this protein. A total of 80 EIF2B4 products are currently listed.

Synonyms:: DDBDRAFT_0189067, DDBDRAFT_0232421, DDB_0189067, DDB_0232421, EIF-2B, EIF2B, EIF2B4, EIF2BD, EIF2Bdelta, MGC146592, si:ch211-101l18.4, wu:fb54a09, zgc:110790

list all antibodies	Gene Name	GeneID	UniProt
	EIF2B4	13667	Q61749
	EIF2B4	117019	Q63186
	EIF2B4	8890	Q9UI10
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anti-Rat (Rattus) EIF2B4 Antibodies:

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Relevant Pathways for anti-EIF2B4 Antibodies

Methionine Biosynthetic Process

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Top referenced anti-EIF2B4 Antibodies

Human Polyclonal EIF2B4 Primary Antibody for ELISA, WB - ABIN4307573 : Wu, Pan, Du, Wang, Gu, Gao, Li, Leng, Qin, Wu, Jiang: Identification of novel EIF2B mutations in Chinese patients with vanishing white matter disease. in Journal of human genetics 2009 (PubMed)

More Antibodies against EIF2B4 Interaction Partners

Human Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa (EIF2B4) interaction partners

A novel missense mutation within EIF2B4 is associated with vanishing white matter disease.
demonstrate that DAP5 associates with eIF2beta and eIF4AI to stimulate IRES-dependent translation of cellular mRNAs
The functional effects of selected vanishing white matter disease mutations in EIF2B2-5 by coexpressing mutated and wild-type subunits in human cells.
analysis of developmental splicing deregulation in leukodystrophies related to EIF2B mutations
A mutation .626G>A [p.Arg209Gln] in exon 7 and c.1399C>T [p.Arg467Trp] in exon 13 of the EIF2B4-Gens.
Data demonstrate that cellular response resulting from eIF2alpha phosphorylation is attenuated in several cancer cell lines, and correlates with the expression of a specific isoform of a regulatory eIF2B subunit, eIF2Bdelta variant 1 (V1).
These results validate the measurement of eIF2B GEF activity in patients' transformed-lymphocytes as an important tool for the diagnosis of eIF2B-related disorders.
A unique EIF2B mutation spectrum in Chinese Vanishing white matter patients was shown.
Mutation in EIF2B4 causes childhood ataxia with central nervous system hypomyelination/ vanishing white matter leukodystrophy.
We report for the first time that in vitro fertilization and embryo transfer can lead to a successful procreation in patients with OLD related to EIF2B mutations.
This study describe here a case suggestive of ovarioleukodistrophy carrying no eIF2B mutations.
A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of EIF-2B, is reported.
Study reports 9 novel mutations in EIF2B genes in 8 patients, increasing number of known mutations to more than 120. Using homology modeling, analyzed the impact of novel mutations on the 5 subunits of eIF2B protein (alpha, beta, gamma, delta, epsilon)
The authors suspected VWM and sequenced the genes EIF2B1-5, which revealed one heterozygous mutation in EIF2B4.
We describe the first Chinese patient with typical clinical and radiological features genetically confirmed to have vanishing white matter disease for a mutation in EIF2B4.

EIF2B4 Antigen Profile

Antigen Summary

Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with EIF2B4

eukaryotic translation initiation factor 2B subunit delta (EIF2B4) antibody
eukaryotic translation initiation factor 2B subunit delta L homeolog (eif2b4.L) antibody
eukaryotic translation initiation factor 2B, subunit 4 delta (eif2b4) antibody
eukaryotic translation initiation factor 2B subunit delta (eif2b4) antibody
eIF2B GDP-GTP exchange factor (eIF2b4) antibody
eukaryotic translation initiation factor 2B, subunit 4 delta (Eif2b4) antibody
eukaryotic translation initiation factor 2B subunit delta (Eif2b4) antibody

DDBDRAFT_0189067 antibody
DDBDRAFT_0232421 antibody
DDB_0189067 antibody
DDB_0232421 antibody
EIF-2B antibody
EIF2B antibody
EIF2B4 antibody
EIF2BD antibody
EIF2Bdelta antibody
MGC146592 antibody
si:ch211-101l18.4 antibody
wu:fb54a09 antibody
zgc:110790 antibody

Protein level used designations for EIF2B4

eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa , translation initiation factor eIF-2B subunit delta , translation initiation factor eIF2B delta subunit , translation initiation factor eIF-2B subunit delta-like , eIF-2B GDP-GTP exchange factor subunit delta , eukaryotic translation initiation factor 2B subunit 4 delta , translation initiation factor eIF-2b delta subunit

GENE ID	SPECIES
425800	Gallus gallus
459099	Pan troglodytes
475702	Canis lupus familiaris
496301	Xenopus laevis
541548	Danio rerio
700322	Macaca mulatta
779817	Xenopus (Silurana) tropicalis
8627814	Dictyostelium discoideum AX4
100055283	Equus caballus
100412065	Callithrix jacchus
100441987	Pongo abelii
100580961	Nomascus leucogenys
13667	Mus musculus
117019	Rattus norvegicus
8890	Homo sapiens
521926	Bos taurus
100009560	Oryctolagus cuniculus

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Show all anti-Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa (EIF2B4) Antibodies with Pubmed References

Human Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa (EIF2B4) interaction partners

Antigen Summary

Alternative names and synonyms associated with EIF2B4

Protein level used designations for EIF2B4