EIF2B4 antibody

Catalog No. ABIN7468324

Product Details anti-EIF2B4 Antibody

Target: EIF2B4 (Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa (EIF2B4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2B4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human EIF2B delta. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.61 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for EIF2B4

Target: EIF2B4 (Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa (EIF2B4))

Alternative Name: eukaryotic translation initiation factor 2B subunit delta (EIF2B4 Products)

Synonyms: wu:fb54a09 antibody, zgc:110790 antibody, si:ch211-101l18.4 antibody, MGC146592 antibody, DDBDRAFT_0189067 antibody, DDBDRAFT_0232421 antibody, DDB_0189067 antibody, DDB_0232421 antibody, Eif2b antibody, EIF-2B antibody, EIF2B antibody, EIF2Bdelta antibody, EIF2B4 antibody, EIF2BD antibody, eukaryotic translation initiation factor 2B subunit delta antibody, eukaryotic translation initiation factor 2B subunit delta L homeolog antibody, eukaryotic translation initiation factor 2B, subunit 4 delta antibody, eIF2B GDP-GTP exchange factor antibody, EIF2B4 antibody, eif2b4.L antibody, eif2b4 antibody, eIF2b4 antibody, Eif2b4 antibody

Background:

Synonyms: eukaryotic translation initiation factor 2B subunit delta , EIF-2B , EIF2B , EIF2Bdelta

Background: Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Molecular Weight: 58 kDa

Gene ID: 8890

UniProt: Q9UI10

Pathways: Methionine Biosynthetic Process