EIF2B4 antibody (Middle Region)

Catalog No. ABIN952044

Product Details anti-EIF2B4 Antibody

Target: EIF2B4 (Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa (EIF2B4))

Binding Specificity: AA 153-183, Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2B4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to EIF2B4.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 153-183 amino acids from the Central region of human EIF2B4

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for EIF2B4

Target: EIF2B4 (Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa (EIF2B4))

Alternative Name: EIF2B4 / EIF2BD (EIF2B4 Products)

Synonyms: wu:fb54a09 antibody, zgc:110790 antibody, si:ch211-101l18.4 antibody, MGC146592 antibody, DDBDRAFT_0189067 antibody, DDBDRAFT_0232421 antibody, DDB_0189067 antibody, DDB_0232421 antibody, Eif2b antibody, EIF-2B antibody, EIF2B antibody, EIF2Bdelta antibody, EIF2B4 antibody, EIF2BD antibody, eukaryotic translation initiation factor 2B subunit delta antibody, eukaryotic translation initiation factor 2B subunit delta L homeolog antibody, eukaryotic translation initiation factor 2B, subunit 4 delta antibody, eIF2B GDP-GTP exchange factor antibody, EIF2B4 antibody, eif2b4.L antibody, eif2b4 antibody, eIF2b4 antibody, Eif2b4 antibody

Background: Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].Synonyms: Translation initiation factor eIF-2B subunit delta, eIF-2B GDP-GTP exchange factor subunit delta

Molecular Weight: 57557 Da

Gene ID: 8890

NCBI Accession: NP_001029288

Pathways: Methionine Biosynthetic Process