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Neuroligin 1/2/3/4 antibody (AA 1-695)

The Mouse Monoclonal anti-Neuroligin 1/2/3/4 antibody has been validated for IP, ELISA and WB. It is suitable to detect Neuroligin 1/2/3/4 in samples from Mouse and Rat. There are 6+ publications available.
Catalog No. ABIN1742285

Quick Overview for Neuroligin 1/2/3/4 antibody (AA 1-695) (ABIN1742285)

Target

Neuroligin 1/2/3/4 (NLGN1/2/3/4)

Reactivity

Mouse, Rat

Host

Mouse

Clonality

Monoclonal

Application

Immunoprecipitation (IP), ELISA, Western Blotting (WB)

Clone

4F9
  • Binding Specificity

    AA 1-695

    Specificity

    Recognizes rat and mouse neuroligins 1-3 and rat neuroligin 4.

    Immunogen

    Recombinant protein of rat neuroligin 1 containing the extracellular sequence (aa 1-695).

    Isotype

    IgG2a
  • Application Notes

    WB: 1:1000, ICC: not recommended IHC: not recommended

    Comment

    ELISA: Suitable as capture antibody for sandwich-ELISA as detector antibody (protocol for sandwich-ELISA).

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    For reconstitution add 100µl H2O to get a 1mg/ml solution in PBS.

    Buffer

    PBS. Albumin and azide were added for stabilization.

    Preservative

    Sodium azide

    Handling Advice

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    Storage

    -20 °C

    Storage Comment

    Reconstitute and aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized.
  • Jadhav, Katina, Kovac, Kazmerova, Novak, Zilka: "Truncated tau deregulates synaptic markers in rat model for human tauopathy." in: Frontiers in cellular neuroscience, Vol. 9, pp. 24, (2015) (PubMed).

    Fujita-Jimbo, Tanabe, Yu, Kojima, Mori, Li, Iwamoto, Yamagata, Momoi, Momoi: "The association of GPR85 with PSD-95-neuroligin complex and autism spectrum disorder: a molecular analysis." in: Molecular autism, Vol. 6, pp. 17, (2015) (PubMed).

    Vasileva, Horstmann, Geumann, Gitler, Kuner: "Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission." in: The European journal of neuroscience, Vol. 36, Issue 8, pp. 3005-20, (2012) (PubMed).

    Bottos, Destro, Rissone, Graziano, Cordara, Assenzio, Cera, Mascia, Bussolino, Arese: "The synaptic proteins neurexins and neuroligins are widely expressed in the vascular system and contribute to its functions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 49, pp. 20782-7, (2010) (PubMed).

    De Jaco, Comoletti, Kovarik, Gaietta, Radic, Lockridge, Ellisman, Taylor: "A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the alpha,beta-hydrolase fold protein family." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9667-76, (2006) (PubMed).

    Chih, Engelman, Scheiffele: "Control of excitatory and inhibitory synapse formation by neuroligins." in: Science (New York, N.Y.), Vol. 307, Issue 5713, pp. 1324-8, (2005) (PubMed).

  • Target

    Neuroligin 1/2/3/4 (NLGN1/2/3/4)

    Alternative Name

    Neuroligin
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