Browse our anti-CRHR2 (CRHR2) Antibodies

Horse (Equine) Corticotropin Releasing Hormone Receptor 2 (CRHR2) interaction partners

1. The expression of UCN, CRHR1, CRHR2 and CRHBP by immunohistochemistry, Western blot and reverse transcription with the polymerase chain reaction (RT-PCR) in the horse thyroid gland, was investigated

Human Corticotropin Releasing Hormone Receptor 2 (CRHR2) interaction partners

1. CRF2 signaling induces alterations in both the epithelium permeability and the differentiation of human colonic carcinoma cell lines.

2. Data show that corticotropin releasing hormone receptor 2 (Crhr2) protein is abundantly expressed in the heart, and plasma Ucn2 levels were higher in patients with heart failure compared to healthy controls, indicating that endogenous Crhr2 is associated with heart failure.

3. Taken together, our data indicate that sex shows significant interaction with genotype and Ucn1 during colitis. Human duodenal and colonic biopsies revealed that sex-specific differences exist in levels of CRF receptors and Ucn1 expression in patients with CD compared with the matched non-IBD subjects. To conclude, Ucn1 mediates sex-specific immune and cellular signaling responses via CRF2, emphasizing the need for inclus

4. In deep infiltrating endometriotic lesions, CRH (show CRH Antibodies), Ucn (show UCN Antibodies) and CRH-R2 mRNA levels were significantly higher than in ovarian endometrioma.

5. Endogenous CRF (show CRH Antibodies) may be involved in the pathogenesis of ischemia/reperfusion-induced enteritis, possibly via the activation of peripheral CRF (show CRH Antibodies) receptor 2

6. This study showed that two CRHR2 variants (rs4722999-C and rs12701020-C) in BPD (show MOD(MDG4) Antibodies) subjects with sexual and physical abuse.

7. found associations between CRHR2 genotypes and haplotypes and negative emotion in IBS patients and controls

8. Wound healing and signal transducer and activator of transcription 3 activity were elevated in CRHR2-overexpressing cells after urocortin 2 and IL-6 treatment, suggesting advanced healing progression

9. This study demonstrated that CRF2 Receptor Deficiency Eliminates the Long-Lasting Vulnerability of Motivational States Induced by Opiate Withdrawal.

10. D1 and CRF2 alpha receptors are capable of heterodimerization in living cells. D1 /CRF2 alpha receptor heteromerization might account, at least in part, for the complex physiological interactions established between dopamine and CRH (show CRH Antibodies).

Mouse (Murine) Corticotropin Releasing Hormone Receptor 2 (CRHR2) interaction partners

1. CRFR2-expressing neurons within the posterior bed nucleus of the stria terminalis (pBNST) send dense inhibitory projections to other stress-related brain regions. Local CRFR2 activation by urocortin 3 (show UCN3 Antibodies) depolarized the cells, increased the neuronal input resistance and increased firing of action potentials. Optogenetic activation of CRFR2 neurons in the pBNST decreased anxiety and attenuated stress responses.

2. Urocortin 2 (show UTS2 Antibodies) acts on gonadotrophs expressing the corticotropin-releasing factor (show CRH Antibodies) type 2 receptor, and inhibits the production of gonadotropins in the pituitary gonadotropic tumor cells.

3. Results indicate that corticotropin releasing hormone receptor 2 (Crhr2) is highly expressed in cardiomyocytes, and cardiomyocyte-specific deletion of Crhr2 protected mice from pressure overload-induced cardiac dysfunction.

4. findings collectively suggest that the MeA (show MEA1 Antibodies) Ucn3 (show UCN3 Antibodies)-CRF-R2 system modulates the ability of mice to cope with social challenges

5. Study suggests that selective CRF2 receptor agonists urocortin 2 (show UTS2 Antibodies) and 3 could be used as a therapy in nicotine addiction.

6. Study demonstrated that CRF1 receptor (show CRHR1 Antibodies)-deficiency prolongs whereas CRF2 receptor-deficiency shortens the duration of recognition memory deficits induced by morphine discontinuation, unraveling opposite roles for the two known CRF (show CRH Antibodies) receptor subtypes in cognitive dysfunction associated with opiate withdrawal.

7. results indicate that long-term UVA eye irradiation led to increased gp91phox (show CYBB Antibodies)-derived ROS (show ROS1 Antibodies) in the brain and the increased expression of urocortin 2 (show UTS2 Antibodies) and CRHR (show CRHR1 Antibodies) type 2, resulting in photoaging; however, further studies are needed to confirm these findings

8. Crhr2(-/-) mice showed increased mortality in the dextran sodium sulfate healing protocol

9. the inhibitory effect of CRFR2 signaling on insulin (show INS Antibodies) action is mediated by cAMP in a mammalian target of rapamycin (show FRAP1 Antibodies)-dependent manner.

10. This study aims to investigate the cellular localization of CRF (show CRH Antibodies) and UCNs in the ileum and to explore whether and how this cellular expression is altered in conditions of intestinal Schistosoma mansoni-induced inflammation.

Cow (Bovine) Corticotropin Releasing Hormone Receptor 2 (CRHR2) interaction partners

1. These results suggest that a regulatory system exists in the bovine thyroid gland based on UCN (show UCN Antibodies), CRHR1 (show CRHR1 Antibodies) and CRHR2 and that UCN (show UCN Antibodies) plays a role in the regulation of thyroid physiological functions through an autocrine/paracrine mechanism.

2. CRHR1 (show CRHR1 Antibodies) and CRHR2 are expressed in the bovine adrenal gland.

Pig (Porcine) Corticotropin Releasing Hormone Receptor 2 (CRHR2) interaction partners

1. CRFr1 (show CRHR1 Antibodies) activation mediates intestinal mucosa barrier dysfunction and hypersecretion in early-weaned piglets, whereas CRFr2 activation may be responsible for novel protective properties in the porcine intestine in response to early life stress.