anti-DUSP4 Antibodies

Protein Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.

Alternative names and synonyms associated with DUSP4

• dual specificity phosphatase 4 (dusp4) antibody
• dual specificity phosphatase 4 (DUSP4) antibody
• dual specificity phosphatase 4 S homeolog (dusp4.S) antibody
• dual specificity phosphatase 4 (Dusp4) antibody

• 2700078F24Rik antibody
• AI844617 antibody
• BB104621 antibody
• DUSP4 antibody
• E130306H24Rik antibody
• Show all synonym aliases
• HVH2 antibody
• MGC131045 antibody
• Mkp-2 antibody
• Mkp2 antibody
• TYP antibody
• zgc:55423 antibody

Protein level used designations for DUSP4

dual specificity protein phosphatase 4 , dual specificity phosphatase 4 , MAP kinase phosphatase 2 , VH1 homologous phosphatase 2 , dual specificity protein phosphatase hVH2 , mitogen-activated protein kinase phosphatase 2 , serine/threonine specific protein phosphatase