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anti-Human DUSP4 Antibodies:
anti-Mouse (Murine) DUSP4 Antibodies:
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Frog Monoclonal DUSP4 Primary Antibody for IF, IP - ABIN968214
Black, Walker, Clark, MacLaren, Gillespie: Cell transformation by v-Jun deactivates ERK MAP kinase signalling. in Oncogene 2002
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Human Polyclonal DUSP4 Primary Antibody for IHC (p), IHC - ABIN446872
Manzano, Martinez-Navarro, Forteza, Brugarolas: Microarray phosphatome profiling of breast cancer patients unveils a complex phosphatase regulatory role of the MAPK and PI3K pathways in estrogen receptor-negative breast cancers. in International journal of oncology 2014
Human Monoclonal DUSP4 Primary Antibody for ELISA, WB - ABIN560663
Lee, Huang, Lee, Lee, Ryu, Kim, Kim, Kim, Joung, Kim, Shong, Jo: Dual specificity phosphatase 6 as a predictor of invasiveness in papillary thyroid cancer. in European journal of endocrinology / European Federation of Endocrine Societies 2012
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.
dual specificity protein phosphatase 4
, dual specificity phosphatase 4
, MAP kinase phosphatase 2
, VH1 homologous phosphatase 2
, dual specificity protein phosphatase hVH2
, mitogen-activated protein kinase phosphatase 2
, serine/threonine specific protein phosphatase