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anti-Human IL1R2 Antibodies:
anti-Mouse (Murine) IL1R2 Antibodies:
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Human Monoclonal IL1R2 Primary Antibody for FACS, ELISA - ABIN2688929
Bessis, Guéry, Mantovani, Vecchi, Sims, Fradelizi, Boissier: The type II decoy receptor of IL-1 inhibits murine collagen-induced arthritis. in European journal of immunology 2000
Show all 2 Pubmed References
Mouse (Murine) Polyclonal IL1R2 Primary Antibody for CyTOF, FACS - ABIN4899247
OConnor, Sherry, Guest, Freund et al.: Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with ... in Journal of immunology (Baltimore, Md. : 1950) 2007
Human Monoclonal IL1R2 Primary Antibody for FACS - ABIN4895805
Mattiola, Pesant, Tentorio, Molgora, Marcenaro, Lugli, Locati, Mavilio: Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways. in Journal of immunology (Baltimore, Md. : 1950) 2015
Human Polyclonal IL1R2 Primary Antibody for ICC, IF - ABIN442643
Asaoka, Island, Tryphonopoulos, Selvaggi, Moon, Tekin, Amador, Levi, Garcia, Smith, Nishida, Weppler, Tzakis, Ruiz: Characteristic immune, apoptosis and inflammatory gene profiles associated with intestinal acute cellular rejection in formalin-fixed paraffin-embedded mucosal biopsies. in Transplant international : official journal of the European Society for Organ Transplantation 2011
these results reveal that the IL-1 (show IL1A Antibodies)/IL-1R2 axis is differentially regulated in the remitting intestinal mucosa of ulcerative colitis patients
Data show that all the six inflammation-related CpG-SNPs genotypes including IL1B (show IL1B Antibodies) rs16944, IL1R2 rs2071008, PLA2G7 (show Lp-PLA2 Antibodies) rs9395208, FAM5C rs12732361, CD40 (show CD40 Antibodies) rs1800686, and CD36 (show CD36 Antibodies) rs2065666 were associated with coronary heart disease (CHD (show CHDH Antibodies)), suggesting an important role of inflammation in the risk of CHD (show CHDH Antibodies).
Expression level of IL1R2 was down regulated in cervical squamous cell carcinoma.
No significant differences in the lymphocyte mRNA levels of IL-1R2, IL-6R, and Gp130 were observed between MDD patients and NC. These studies suggest abnormal gene expression of these cytokines and their membrane-bound receptors in the lymphocytes of MDD patients, and that their mRNA expression levels in the lymphocytes could be a useful biomarker for depression.
IL1R2 rs2310173 genotype GT was mildly protective against ankylosing spontylitis only in HLA-B27-negative patients.
IL1R2 hypomethylation and androgen receptor (show AR Antibodies) hypermethylation may constitute an important determinant of disease severity, whereas NPR2 (show NPRL2 Antibodies) hypomethylation and SP140 (show SP140 Antibodies) hypermethylation may provide a biomarker for vulnerability to excessive daytime sleepiness in Obstructive Sleep Apnea
This is the first detection that the genetic variation rs2302589 in IL-1R2 gene was associated with ankylosing spondylitis in Northern Han Chinese.
Data show that interleukin-1 receptor type 2 (IL1R2) forms a complex with c-Fos proto-oncogene protein and activates the interleukin-6 (IL-6 (show IL6 Antibodies)) and vascular endothelial growth factor A (VEGF-A (show VEGFA Antibodies)) promoters.
Cerebrospinal fluid soluble interleukin-1 Receptor II, but not log interleukin-6 (show IL6 Antibodies), levels were positively correlated with a composite measure of aggression.
results suggested that IL1R2 could have oncogenic potential in osteosarcoma
Our data demonstrate that the decoy receptor IL-1R2 plays an important inhibitory role in local IL-1 (show IL1A Antibodies)- and neutrophil-dependent tissue inflammation
Data indicate that a disintegrin and metallopeptidase domain 17 (ADAM17 (show ADAM17 Antibodies)) regulates interleukin (IL)-1 (show IL1A Antibodies) signaling via cleavage of IL-1 (show IL1A Antibodies) receptor type 2 (IL-1R2).
IL-1 (show IL1A Antibodies) receptor type 2 suppresses collagen-induced arthritis by inhibiting IL-1 (show IL1A Antibodies) signal on macrophages.
Interleukin-1 receptor type II is significantly upregulated in decidual cells close to the embryo during days 5 to 8 of pregnancy.
Data show that bee venom detected by inflammasome and trigger activation of caspase-1 (show CASP1 Antibodies) and secretion of proinflammatory cytokine IL-1beta (show IL1B Antibodies) is pyrin domain-containing 3 NLRP3 (show NLRP3 Antibodies), apoptosis-associated speck-like protein ASC (show STS Antibodies), and IL-1 (show IL1A Antibodies) receptor dependent.
inoculation of young CD4 (show CD4 Antibodies)(+) T cells or a fetal thymus graft led to down regulation of the interleukin 1 receptor type II (IL-1R2) gene in CD4 (show CD4 Antibodies)(+) T cells and reduced age-related hearing loss
BACE1 (show BACE Antibodies) and BACE2 (show BACE2 Antibodies) may act as alternative alpha-secretase-like proteases in proteolytic processing of IL-1R2 and APP (show APP Antibodies)
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.
interleukin-1 receptor type 2
, soluble type II IL-1 receptor
, CD121 antigen-like family member B
, IL-1 type II receptor
, antigen CDw121b
, interleukin 1 receptor type II variant 3
, interleukin-1 receptor beta
, interleukin-1 receptor type II
, type II interleukin-1 receptor, beta
, IL-1 receptor beta chain