IL1R2 antibody (AA 79-219)

Catalog No. ABIN7156768

Product Details anti-IL1R2 Antibody

Target: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Binding Specificity: AA 79-219

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1R2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Interleukin-10 receptor subunit beta protein (79-219AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IL1R2

Target: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Alternative Name: IL1RB (IL1R2 Products)

Synonyms: CD121b antibody, CDw121b antibody, IL-1R-2 antibody, IL-1RT-2 antibody, IL-1RT2 antibody, IL1R2c antibody, IL1RB antibody, Il1r-2 antibody, IL-1R2 antibody, interleukin 1 receptor type 2 antibody, interleukin 1 receptor, type II antibody, interleukin-like antibody, IL1R2 antibody, Il1r2 antibody, KK34 antibody

Background:

Background: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.

Aliases: Cd210 antibody, CDw210b antibody, CRF2 4 antibody, CRF2-4 antibody, CRFB4 antibody, Cytokine receptor class II antibody, Cytokine receptor class II CRF2 4 antibody, Cytokine receptor class-II member 4 antibody, Cytokine receptor family 2 member 4 antibody, Cytokine receptor family II member 4 antibody, D21S58 antibody, D21S66 antibody, I10R2_HUMAN antibody, IL-10 receptor subunit beta antibody, IL-10R subunit 2 antibody, IL-10R subunit beta antibody, IL-10R2 antibody, IL-10RB antibody, IL10R2 antibody, IL10RB antibody, Interleukin 10 receptor beta antibody, Interleukin-10 receptor subunit 2 antibody, Interleukin-10 receptor subunit beta antibody

UniProt: Q08334

Pathways: NF-kappaB Signaling