Recombinant IL1R2 antibody (Extracellular Domain)

Catalog No. ABIN1169422

This Mouse Monoclonal antibody specifically detects IL1R2 in ELISA and FACS. It exhibits reactivity toward Mouse.

Quick Overview for Recombinant IL1R2 antibody (Extracellular Domain) (ABIN1169422)

Target: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL1R2 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: Praxy-1-1

Product Details anti-IL1R2 Antibody

Binding Specificity: Extracellular Domain

Specificity: Recognizes mouse IL-1R2.

Cross-Reactivity: Mouse (Murine)

Purification: Purified from HEK 293 cell culture supernatant.

Purity: >95 % (SDS-PAGE)

Endotoxin Level: <0.01EU/μg purified protein (LAL-test, Lonza).

Immunogen: Recombinant mouse IL-1R2 (extracellular domain).

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

IL-1R2 (mouse) monoclonal antibody (recombinant) (Praxy-1-1) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the mouse IgG2b Fc domain.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 month after receipt when stored at +4°C. Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for IL1R2

Target: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Alternative Name: IL-1R2

Background: The inflammatory actions of IL-1alpha and beta depend on their interaction with its receptor, IL-1R1, and can be negatively controlled by several inhibitors such as IL-1Ra, IL-1R type 2 (IL-1R2), SIGIRR and the soluble form of IL-1 receptor accessory protein (IL-1RAcP). IL-1R2 neutralizes IL-1 either as a surface decoy receptor or in a cleaved and secreted form. IL-1R2 is expressed on B cells, on neutrophils and on in vitro expanded human Tregs.

UniProt: P27931

Pathways: NF-kappaB Signaling