IL1R2 antibody (Interleukin 1 Receptor, Type II) (Extracellular Domain)

Details for Product anti-IL1R2 Antibody No. ABIN1169422, Supplier: Log in to see
Antigen
  • CD121b
  • CDw121b
  • IL-1R-2
  • IL-1RT-2
  • IL-1RT2
  • IL1R2c
  • IL1RB
  • Il1r-2
  • interleukin 1 receptor type 2
  • interleukin 1 receptor, type II
  • IL1R2
  • Il1r2
Alternatives
anti-Human IL1R2 antibody for Enzyme Immunoassay
Epitope
Extracellular Domain
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Reactivity
Mouse (Murine)
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Host
Mouse
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Antibody Type
Recombinant Antibody
Clonality (Clone)
Monoclonal ()
Conjugate
This IL1R2 antibody is un-conjugated
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Application
Flow Cytometry (FACS), ELISA
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Options
Supplier
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Supplier Product No.
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Immunogen Recombinant mouse IL-1R2 (extracellular domain).
Clone Praxy-1-1
Isotype IgG2b
Specificity Recognizes mouse IL-1R2.
Cross-Reactivity Mouse (Murine)
Purification Purified from HEK 293 cell culture supernatant.
Purity >95 % (SDS-PAGE)
Endotoxin Level <0.01EU/μg purified protein (LAL-test, Lonza).
Alternative Name IL-1R2 (IL1R2 Antibody Abstract)
Background The inflammatory actions of IL-1alpha and beta depend on their interaction with its receptor, IL-1R1, and can be negatively controlled by several inhibitors such as IL-1Ra, IL-1R type 2 (IL-1R2), SIGIRR and the soluble form of IL-1 receptor accessory protein (IL-1RAcP). IL-1R2 neutralizes IL-1 either as a surface decoy receptor or in a cleaved and secreted form. IL-1R2 is expressed on B cells, on neutrophils and on in vitro expanded human Tregs.
UniProt P27931
Pathways NF-kappaB Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Comment

IL-1R2 (mouse) monoclonal antibody (recombinant) (Praxy-1-1) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the mouse IgG2b Fc domain.

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer In PBS containing 10 % glycerol and 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 month after receipt when stored at +4°C. Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-Interleukin 1 Receptor, Type II (IL1R2) (Extracellular Domain) antibody (ABIN1169422) Detection of endogenous mouse IL-1R2 with IL-1R2 (mouse), mAb (rec.) (Praxy-1-1) . Me...
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