Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Mouse (Murine) Antibodies:
anti-Rat (Rattus) Antibodies:
Go to our pre-filtered search.
Human Polyclonal NME3 Primary Antibody for ELISA, WB - ABIN562009
McDermott, Boissan, Lacombe, Steeg, Horak: Nm23-H1 homologs suppress tumor cell motility and anchorage independent growth. in Clinical & experimental metastasis 2008
Human Polyclonal NME3 Primary Antibody for IHC (p), ELISA - ABIN542990
Venturelli, Martinez, Melotti, Casella, Peschle, Cucco, Spampinato, Darzynkiewicz, Calabretta: Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells. in Proceedings of the National Academy of Sciences of the United States of America 1995
Show all 3 Pubmed References
Proinflammatory signaling mediated by innate immunity engagement of flagellin-activated TLR5 in tumor cells results in antitumor effects through NME3 kinase, a positive downstream regulator of flagellin-mediated NFkappaB signaling, enhancing survival for several human cancers.
Given the critical role of mitochondrial dynamics and energy requirements in neuronal development, the homozygous mutation in NME3 is linked to a fatal mitochondrial neurodegenerative disorder.
The ciliopathy-typical manifestations of NME3 depletion in two vertebrate in vivo models, the biochemical association of NME3 with validated NPHPs, and its localization to the basal body reveal a role for NME3 in ciliary function. We conclude that mutations in the NME3 gene may aggravate the ciliopathy phenotypes observed in humans.
Thus Tip60 interacts with RNR and NME3 to provide site-specific synthesis of dNTP for facilitating DNA repair in serum-deprived cells which contain low levels of dNTPs.
Down-regulated DR-nm23 expression is associated with invasion and metastasis in colorectal cancer.
Among genes correlated to nodal metastatic progression, we verified in vitro that NM23-H3 reduced cell motility.
NME3 protein interacts with RHO signaling cascades to impair sperm motility through hyperactivation of SMOK, the wild-type form of the responder.
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
, NDP kinase 3
, NDP kinase C
, non-metastatic cells 3, protein expressed in
, nucleoside diphosphate kinase 3
, nucleoside diphosphate kinase C
, expressed in non-metastatic cells 3
, nucleoside diphosphate kinase DR-nm23