FAS ELISA Kits

Protein Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.

Alternative names and synonyms associated with FAS

• Fas cell surface death receptor (FAS) antibody
• Fas ligand (FASLG) antibody
• tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (YWHAZ) antibody
• Fas (TNF receptor superfamily member 6) (Fas) antibody
• Fas cell surface death receptor (Fas) antibody
• Show all gene names
• Fas cell surface death receptor (fas) antibody

• AI196731 antibody
• ALPS1A antibody
• APO-1 antibody
• APO1 antibody
• APT1 antibody
• Show all synonym aliases
• CD95 antibody
• FAS1 antibody
• FASL antibody
• FASTM antibody
• lpr antibody
• TNFR6 antibody
• Tnfrsf6 antibody
• TNFSF6 antibody

Protein level used designations for FAS

APO-1 cell surface antigen , CD95 antigen , Delta Fas/APO-1/CD95 , FAS 827dupA , FASLG receptor , Fas (TNF receptor superfamily, member 6) , Fas AMA , TNF receptor superfamily member 6 , apoptosis antigen 1 , apoptosis-mediating surface antigen FAS , tumor necrosis factor receptor superfamily member 6 , tumor necrosis factor receptor superfamily, member 6 , fas antigen ligand , tumor necrosis factor (ligand) superfamily, member 6 , tumor necrosis factor ligand superfamily member 6 , Fas antigen , 14-3-3 protein zeta/delta , FAS , KCIP-1 , factor activating exoenzyme S , protein kinase C inhibitor protein 1 , Fas (TNF receptor superfamily member) , apo-1 antigen , lymphoproliferation , Fas antigen (ATP1) , Fas receptor , Tumor necrosis factor receptor superfamily, member 6 , apoptosis (APO-1) antigen 1 ( FAS ), member 6 , Fas receptor CD95