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Human HMGB1 ELISA Kit for Sandwich ELISA - ABIN414391
Zeng, Zhang, Gu, Chen, Jiang, Zhang, Du, Hu, Huang, Wang, Jiang: Clinical relevance of single nucleotide polymorphisms of the high mobility group box 1 protein gene in patients with major trauma in southwest China. in Surgery 2012
Show all 37 Pubmed References
Mouse (Murine) HMGB1 ELISA Kit for Sandwich ELISA - ABIN415379
Wang, Zhang, Lei, Zhou, Ye: The inhibitory effect of lidocaine on the release of high mobility group box 1 in lipopolysaccharide-stimulated macrophages. in Anesthesia and analgesia 2011
Show all 17 Pubmed References
Rat (Rattus) HMGB1 ELISA Kit for Sandwich ELISA - ABIN416082
Hou, Qin, Zheng, Lu, Wang, Peng, Yu, Xin, Ji, Xiong: Severity of sepsis is correlated with the elevation of serum high-mobility group box 1 in rats. in Chinese medical journal 2009
Show all 6 Pubmed References
Human HMGB1 ELISA Kit for Sandwich ELISA - ABIN455352
Albayrak, Uyanik, Cerrah, Altas, Dursun, Demir, Uslu: Is HMGB1 a new indirect marker for revealing fibrosis in chronic hepatitis and a new therapeutic target in treatment? in Viral immunology 2010
Show all 2 Pubmed References
Mouse (Murine) HMGB1 ELISA Kit for Sandwich ELISA - ABIN1115430
Li, Chen, Wang, Nie, Huang, Yuan, Sun, Shu, Wang, Gong, Tang: Protective effects of hesperidin on concanavalin A-induced hepatic injury in mice. in International immunopharmacology 2014
Mouse (Murine) HMGB1 ELISA Kit for Sandwich ELISA - ABIN366368
Shen, Fang, Wu, He, Ding, Liu: Repeated inhalation of sevoflurane inhibits airway inflammation in an OVA-induced mouse model of allergic airway inflammation. in Respirology (Carlton, Vic.) 2014
Dog (Canine) HMGB1 ELISA Kit for Sandwich ELISA - ABIN414234
Kuleš, Gotić, Mrljak, Barić Rafaj: Blood markers of fibrinolysis and endothelial activation in canine babesiosis. in BMC veterinary research 2017
Human HMGB1 ELISA Kit for Competition ELISA - ABIN511375
Zeng, Xiang, Lin, Zhang, Liu, Kong, Gao, Lu, Wu, Yi, Zhong, Xu: Elevated HMGB1-related interleukin-6 is associated with dynamic responses of monocytes in patients with active pulmonary tuberculosis. in International journal of clinical and experimental pathology 2015
Rat (Rattus) HMGB1 ELISA Kit for Sandwich ELISA - ABIN367992
Li, Sun, Li, Xie, Wan, Luo: Oxygen glucose deprivation/reperfusion astrocytes promotes primary neural stem/progenitor cell proliferation by releasing high-mobility group box 1. in Neurochemical research 2014
HMGB1 induced the activation of p38 and nuclear factor-kappaB (NF-kappaB) in TLR4/ primary AVICs, and inhibited p38 and NFkappaB in wildtype AVICs treated with TLR4specific antibodies.
HMGB1 is capable to promote oncogenesis or suppress tumor growth, thus affecting treatment efficacy. [review]
In persons with chronic spinal cord injury, HMGB1 was significantly elevated, compared with uninjured persons.
chaperone-mediated autophagy pathway activation appears to decrease hepatocellular carcinoma susceptibility to apoptosis on irradiation through degradation of HMGB1 protein which reduced p53 (show TP53 ELISA Kits) expression
Taken together, these results suggested that the changes, including ox-LDL/LDL ratio, CD68 (show CD68 ELISA Kits)(+)/RANK(+) cells number, and the levels of RANKL (show TNFSF11 ELISA Kits) and HMGB1 in AS patients, favored osteoclastogenesis.
Increased levels of HMGB1 were significantly correlated with the severity and the time of onset of preeclampsia.
These findings suggest that HMGB1 expressed on the surface of circulating platelets in patients with symptomatic coronary artery disease may not serve as a prognostic biomarker for this disease state.
HMGB1 promoted vascular remodeling and dysfunction by initiating an inflammation cascade during ischemia reperfusion injury.
study suggests that sodium tanshinone IIA sulfonate is an effective agent against hypoxic trophoblast-induced cell injury of HUVEC via targeting HMGB1 release and forms the basis of the development of such a compound in treating Preeclampsia.
LncRNA MALAT-1 increases the expression level of HMGB1 in MM thereby promotes autophagy resulting in the inhibition of apoptosis.
Systemic HMGB-1 levels were significantly elevated in both trauma groups when compared to the sham group. Haemorrhagic shock severity and duration were positively correlated with HMGB-1 levels and compared to baseline values, concentrations remained significantly increased in severe hemorrhage when compared to moderate hemorrhage.
high levels of HMGB1 in the small intestine and its relation to high levels of HMGB1 in plasma of piglets infected with E. coli O55 that suffered from infection correlated with high levels of inflammatory cytokines and bacterial translocation; levels were higher than HMGB1 levels in piglets with mild clinical symptoms
HMGB-1 may participate in the inflammatory response and liver injury in the late stage of acute liver failure
HMGB1 can act as an adjuvant in modulating the bovine immune system and thus lays a foundation for using HMGB1 as an adjuvant in various bovine vaccine preparations.
Single-nucleotide polymorphism in the 3'-untranslated region of the HMGB1 gene affects the binding of target bta-miR (show MYLIP ELISA Kits)-223 and is involved in mastitis.
The mechanisms of interaction of the non-histone chromosomal protein (show HMGB2 ELISA Kits) HMGB1 and linker histone H1 (show H1F0 ELISA Kits) with DNA have been studied using circular dichroism and absorption spectroscopy.
HMGB1 is able to induce considerable changes in DNA structure upon binding even when the amount of the protein directly associated with DNA is low
Interaction between non-histone chromatin protein HMGB1 and linker histone H1 (show H1F0 ELISA Kits)
HMGB-1 might play a role in the pathological thickening of subchondral bone plate/osteophyte formation.
Analysis of mechanical response generated by binding of DNA-bending protein HMGB1 to single tethered 48.5 kb lambda-DNA molecules finds that compaction of DNA increases with increasing HMGB1 concentration.
Thrombomoduln not only binds to HMGB1 but also aids the proteolytic cleavage of HMGB1 by thrombin (show F2 ELISA Kits).
Our data suggest that, apart from the role of D3, TMalpha and TM's D123 (show CDC123 ELISA Kits) require both lectin-like D1 capable of sequestering HMGB1 and EGF (show EGF ELISA Kits)-like D2 responsible for thrombin (show F2 ELISA Kits)-dependent degradation of HMGB1, in abolishing the allodynia caused by exogenous or endogenous HMGB1.
Anti-HMGB1 autoimmunity may potentially play a role in atherogenesis in Apoe (show APOE ELISA Kits)(-/-) mice
These results suggest that HMGB1-modulated TLR5 (show TLR5 ELISA Kits) signaling is responsible for pain hypersensitivity.
mip-2 (show CXCL2 ELISA Kits) siRNA and an anti-MIP-2 (show CXCL2 ELISA Kits) antibody significantly reduced the expression levels of Ccl-2 (show CCL2 ELISA Kits), TLR-4 (show TLR4 ELISA Kits), iNOS (show NOS2 ELISA Kits), IL-6 (show IL6 ELISA Kits), IL-1beta (show IL1B ELISA Kits), HMGB1, and TNF-alpha (show TNF ELISA Kits) in RAW264.7 cells exposed tolipopolysaccharide.
We concluded that fusion of HMGB1 with GFP was immunologically more effective than GFP alone.
HMGB-1 is a late inflammatory mediator of sepsis.
HMGB1 activates the NF-kappaB (show NFKB1 ELISA Kits) and JNK (show MAPK8 ELISA Kits)/p38 (show CRK ELISA Kits) pathways through TLR4 (show TLR4 ELISA Kits)/MyD88 (show MYD88 ELISA Kits)-dependent signaling and induces an inflammatory response in lungs exposed to cigarette smoke.
Data demonstrate that inhibition of HMGB1 reduced inflammatory mediators, leading to increased insulin receptor (show INSR ELISA Kits) signal transduction in retinal endothelial cells grown in high glucose. Secondly, use of glycyrrhizin was an effective therapy against ischemia-reperfusion-induced retinal neuronal and vascular damage.
results strongly implicate the HMGB1-TLR2 (show TLR2 ELISA Kits)/4 axis in the activation of microglia following multiple cortical spreading depression inductions
Zingerone reduces release of HMGB1, sepsis-related mortality, and tissue injury in cecal ligation/puncture model of sepsis.
High mobility group box-1 and nucleosomes might have use as biomarkers for horses with gastrointestinal disease.
Extracellular HMGB-1 is widespread only in synovial membrane from diseased joints in horses with osteoarthritis.
Osteochondral injury was associated with a significant increase in synovial HMGB-1 concentrations in horses with joint injuries, compared with results for clinically normal horses.
Airway pressure release ventilation reduces bronchoalveolar lavage fluid HMGB1 levels and lung water, preserving oxygenation and systemic blood pressure in experimental acute respiratory distress syndrome.
SCARA5 (show SCARA5 ELISA Kits) is an HMGB1 recognition receptor that is negatively involved in HMGB1-mediated inflammation in pufferfish (Tetraodon nigroviridis) and zebrafish (Danio rerio) models.
HMGB1 is a critical factor for brain development, enabling survival and proliferation of neural progenitors that will form the forebrain structures.
a transcriptional regulator that may play a central role in the stabilization and/or assembly of several multifunctional complexes through protein-protein interactions
high-mobility group box 1
, high mobility group protein 1
, sulfoglucuronyl carbohydrate binding protein
, High mobility group protein B1
, high mobility group protein B1
, Sulfoglucuronyl carbohydrate binding protein
, high-mobility group (nonhistone chromosomal) protein 1
, non-histone protein HMG1
, heparin-binding protein p30
, high mobility group 1
, high mobility group protein B1-like protein
, high mobility group 1 protein
, high mobility group protein HMG1
, high mobility group protein B1-like
, High mobility group protein 1
, high mobility group box 1
, HMG box transcription factor 1
, HMG box-containing protein 1
, HMG-box containing protein 1
, high mobility group box transcription factor 1