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anti-Human KIF5B Antibodies:
anti-Mouse (Murine) KIF5B Antibodies:
anti-Rat (Rattus) KIF5B Antibodies:
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Human Polyclonal KIF5B Primary Antibody for IHC, ELISA - ABIN184774
Semiz, Park, Nicoloro, Furcinitti, Zhang, Chawla, Leszyk, Czech: Conventional kinesin KIF5B mediates insulin-stimulated GLUT4 movements on microtubules. in The EMBO journal 2003
Show all 3 Pubmed References
Cow (Bovine) Polyclonal KIF5B Primary Antibody for IHC, WB - ABIN2778184
Diefenbach, Diefenbach, Douglas, Cunningham: The ribosome receptor, p180, interacts with kinesin heavy chain, KIF5B. in Biochemical and biophysical research communications 2004
Show all 2 Pubmed References
Utilizing novel electron cryomicroscopy methods, the authors solved structures of microtubule-attached, dimeric kinesin bound to an ATP analog. They find that under these conditions, the kinesin dimer can attach to the microtubule with either one or two motor domains.
cargo recognition and concurrent activation of kinesin-1 proceed in hierarchical stepwise fashion driven by a dynamic network of inter- and intra-molecular interactions.
BORC and Arl8 (show ARL5B Antibodies) function upstream of two structurally distinct kinesin types: kinesin-1 (KIF5B) and kinesin-3 (KIF1Bbeta and KIF1A (show KIF1A Antibodies)).
KIF5B gene rearrangement plays a role in the pathogenesis of papillary thyroid cancer.
compared to those of brain, on MCF7 microtubules, kinesin-1's processivity is significantly reduced although its velocity is only slightly altered
these observations identify a previously unappreciated role for KIF5B in mediating the Nup358 (show RANBP2 Antibodies) dependent nuclear import of the HIV-1 viral genome during infection.
For Fat3 (show FAT3 Antibodies), the Kif5 (show KIF5A Antibodies)-ID is regulated by alternative splicing, and the timecourse of splicing suggests that the distribution of Fat3 (show FAT3 Antibodies) may switch between early and later stages of retinal development. In contrast, P75NTR (show NGFR Antibodies) binding to Kif5B is enhanced by tyrosine phosphorylation and thus has the potential to be dynamically regulated on a more rapid time scale
Data suggest that light-chain subunits/fragments of kinesin-1 inhibit the pathological aggregation of amyloid(beta).
In this work, we performed normal mode analysis with elastic network model using different conformation of kinesin to determine the effect of tail binding.
KIF5B is essential for Ostm1 (show OSTM1 Antibodies) intracellular dispersion.
High KIF5B expression is associated with Lung Metastasis of Breast Cancer.
It was concluded that selective deletion of Kif5b in adipose tissue exacerbates HFD-induced obesity and its associated metabolic disorders, partly through a decrease in energy expenditure, dysregulation of adipokine secretion, and insulin (show INS Antibodies) signaling.
PI3K-dependent formation of a kinesin-1/Slp3/Rab27b (show RAB27B Antibodies) complex is critical for the microtubule-dependent movement of secretory granules required for mast cell degranulation.
The KIF5B level was up-regulated during 3T3-L1 adipogenesis. This increase in cytosolic KIF5B was synchronized with the induction of adiponectin. Endogenous KIF5B and adiponectin were partially colocalized at the peri (show POSTN Antibodies)-nuclear and cytosolic regions.
results indicate that NCAM (show NCAM1 Antibodies) is delivered to the cell surface through a kinesin-1-mediated transport mechanism in a PAK1 (show PAK1 Antibodies)-dependent manner.
Kif5b expression during mouse kidney development
we showed that the KIF5B-RET (show RET Antibodies) fusion gene is oncogenic in lung alveolar epithelial cells in vivo.
nesprin-dependent recruitment of kinesin-1 to the nuclear envelope through the interaction of a conserved LEWD motif with kinesin light chain might be a general mechanism for cell-type-specific nuclear positioning during development.
KIF5B is critical in suppressing chromosomal instability at the early stages of female meiotic cell development and mitotic cell division.
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity).
kinesin heavy chain
, kinesin-like protein KHC
, Kinesin heavy chain
, kinesin heavy chain isoform 5A
, kinesin family member 5B
, kinesin family member 5A
, kinesin-1 heavy chain
, conventional kinesin heavy chain
, kinesin 1 (110-120kD)
, ubiquitous kinesin heavy chain
, kinesin heavy chain member 5B, ubiquitous