KIF5B antibody (N-Term)

Catalog No. ABIN2778184

Product Details anti-KIF5B Antibody

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF5B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: CNIKVMCRFR PLNESEVNRG DKYIAKFQGE DTVVIASKPY AFDRVFQSST

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against KIF5B. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KIF5B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 963 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-KIF5B antibody (ABIN2778184)

Turner, Cheng, Beckham, Keane, Norris, Liu: "Autophagy is increased in prostate cancer cells overexpressing acid ceramidase and enhances resistance to C6 ceramide." in: Prostate cancer and prostatic diseases, Vol. 14, Issue 1, pp. 30-7, (2011) (PubMed).

Target Details for KIF5B

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Alternative Name: KIF5B (KIF5B Products)

Synonyms: KINH antibody, KNS antibody, KNS1 antibody, UKHC antibody, Khc antibody, AL022807 antibody, Khcs antibody, Kns1 antibody, Ukhc antibody, khc antibody, KIF5A antibody, kinesin family member 5B antibody, kinesin heavy chain antibody, kinesin-1 antibody, kinesin-1 heavy chain antibody, kinesin family member 5B S homeolog antibody, KIF5B antibody, LOC411769 antibody, cgd6_2790 antibody, kin-1 antibody, Tb927.1.1350 antibody, LACBIDRAFT_305999 antibody, Khc antibody, LOC100538629 antibody, Kif5b antibody, kif5b.S antibody

Background: Kinesin is the founding member of a superfamily of microtubule based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation. Kinesin consists of heavy and light chains both of which have been documented to bind a variety of potential linker or cargo proteins. KIF5B is an isoform of kinesin heavy chain.
Alias Symbols: KNS, KINH, KNS1, UKHC
Protein Interaction Partner: ZBTB8A, HUWE1, TAX1BP1, VPS52, PRKAR2B, AURKB, STAU1, UBC, TRIM25, EZH2, PSME1, PSMB7, PSMB6, PSMB5, PSMB4, PSMB3, PSMA5, PSMA4, KLC2, SMEK2, RNF20, ELP2, PTPN23, RABGAP1, COPE, AKAP2, COPS5, NUP50, PSMA2, KLC1, EPB41L1, DIAPH1, CAST, ACACA, YWHAE, CFTR,
Protein Size: 963

Molecular Weight: 110 kDa

Gene ID: 3799

NCBI Accession: NM_004521, NP_004512

UniProt: P33176

Pathways: Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization