KIF5B antibody (N-Term)

Catalog No. ABIN2778184

This Rabbit Polyclonal antibody specifically detects KIF5B in WB, IHC and IP. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Pig and Zebrafish (Danio rerio).It has been mentioned in 1 publication

Quick Overview for KIF5B antibody (N-Term) (ABIN2778184)

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Reactivity: Human, Rat, Mouse, Dog, Cow, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF5B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-KIF5B Antibody

Binding Specificity: N-Term

Purpose: KIF5B Antibody - N-terminal region

Sequence: CNIKVMCRFR PLNESEVNRG DKYIAKFQGE DTVVIASKPY AFDRVFQSST

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against KIF5B. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KIF5B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8103969

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-KIF5B antibody (ABIN2778184)

Turner, Cheng, Beckham, Keane, Norris, Liu: "Autophagy is increased in prostate cancer cells overexpressing acid ceramidase and enhances resistance to C6 ceramide." in: Prostate cancer and prostatic diseases, Vol. 14, Issue 1, pp. 30-7, (2011) (PubMed).

Target Details for KIF5B

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Alternative Name: KIF5B

Background:

Background Information: Kinesin is the founding member of a superfamily of microtubule based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation. Kinesin consists of heavy and light chains both of which have been documented to bind a variety of potential linker or cargo proteins. KIF5B is an isoform of kinesin heavy chain.

Gene Name: Kinesin family member 5B

Alternative Symbols: KNS, KINH, KNS1, UKHC, HEL-S-61

Protein Name: Kinesin-1 heavy chain

Molecular Weight: 110kDa

Gene ID: 3799

NCBI Accession: NP_004512

UniProt: P33176

Pathways: Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization