Corin, Serine Peptidase (CORIN) (C-Term) Peptide
CORIN
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN1541048
Quick Overview for Corin, Serine Peptidase (CORIN) (C-Term) Peptide (ABIN1541048)
Target
Corin (CORIN)
(Corin, Serine Peptidase (CORIN))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- MGNKMPFKLQ EGEVRIIPLE QCQSYFDMKT ITNRMICAGY ESGTVDSCMG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Corin Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Corin (CORIN) (Corin, Serine Peptidase (CORIN))
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Background
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Corin is a Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. It converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Corin also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide.
Alias Symbols: AV273130, Lrp4
Protein Size: 1113 -
Molecular Weight
- 123 kDa
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Gene ID
- 53419
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NCBI Accession
- NM_016869, NP_058565
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UniProt
- Q9Z319
Target
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