Retinoblastoma Binding Protein 4 (RBBP4) (C-Term) Peptide
RBBP4
Reactivity: Human, Mouse
Host: Synthetic
WB, BP
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- Target See all Retinoblastoma Binding Protein 4 (RBBP4) products
- Retinoblastoma Binding Protein 4 (RBBP4)
- Protein Region
- C-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Western Blotting (WB), Blocking Peptide (BP)
- Sequence
- TAKISDFSWN PNEPWVICSV SEDNIMQVWQ MAENIYNDED PEGSVDPEGQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Rbbp4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Retinoblastoma Binding Protein 4 (RBBP4)
- Background
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Rbbp4 is a core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling, and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development, and the NURF (nucleosome remodeling factor) complex.
Alias Symbols: mRbAp48
Protein Size: 425 - Molecular Weight
- 47 kDa
- Gene ID
- 19646
- NCBI Accession
- NM_009030, NP_033056
- UniProt
- Q60972
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