Muscarinic Acetylcholine Receptor M1 (CHRM1) (C-Term) Peptide
CHRM1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN1541301
Quick Overview for Muscarinic Acetylcholine Receptor M1 (CHRM1) (C-Term) Peptide (ABIN1541301)
Target
CHRM1
(Muscarinic Acetylcholine Receptor M1 (CHRM1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- VKRPTKKGRD RAGKGQKPRG KEQLAKRKTF SLVKEKKAAR TLSAILLAFI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CHRM1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))
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Background
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The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
Alias Symbols: HM1, M1, M1R, MGC30125
Protein Size: 460 -
Molecular Weight
- 51 kDa
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Gene ID
- 1128
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NCBI Accession
- NM_000738, NP_000729
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UniProt
- P11229
Target
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