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Sec61 alpha 1 Subunit (SEC61A1) (C-Term) Peptide

SEC61A1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN1541381

Quick Overview for Sec61 alpha 1 Subunit (SEC61A1) (C-Term) Peptide (ABIN1541381)

Target

SEC61A1 (Sec61 alpha 1 Subunit (SEC61A1))

Origin

Human

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    TWIEVSGSSA KDVAKQLKEQ QMVMRGHRET SMVHELNRYI PTAAAFGGLC

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-SEC61A1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    SEC61A1 (Sec61 alpha 1 Subunit (SEC61A1))

    Background

    The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits.

    Alias Symbols: HSEC61, SEC61, SEC61A

    Protein Size: 476

    Molecular Weight

    52 kDa

    Gene ID

    29927

    NCBI Accession

    NM_013336, NP_037468

    UniProt

    P61619
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