Sec61 alpha 1 Subunit (SEC61A1) (C-Term) Peptide
Quick Overview for Sec61 alpha 1 Subunit (SEC61A1) (C-Term) Peptide (ABIN1541381)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- TWIEVSGSSA KDVAKQLKEQ QMVMRGHRET SMVHELNRYI PTAAAFGGLC
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SEC61A1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SEC61A1 (Sec61 alpha 1 Subunit (SEC61A1))
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Background
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The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits.
Alias Symbols: HSEC61, SEC61, SEC61A
Protein Size: 476 -
Molecular Weight
- 52 kDa
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Gene ID
- 29927
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NCBI Accession
- NM_013336, NP_037468
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UniProt
- P61619
Target
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