Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN) (Middle Region) Peptide
KNSTRN
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN1542205
Quick Overview for Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN) (Middle Region) Peptide (ABIN1542205)
Target
KNSTRN
(Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- TDTATRRNVR KGYKPLSKQK SEEELKDKNQ LLEAVNKQLH QKLTETQGEL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-C15orf23 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
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Background
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C15orf23 is an essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. It promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.
Alias Symbols: SKAP, TRAF4AF1, C15orf23
Protein Size: 316 -
Molecular Weight
- 35 kDa
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Gene ID
- 90417
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NCBI Accession
- NM_033286, NP_150628
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UniProt
- Q9Y448
Target
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