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Eukaryotic Translation Initiation Factor 6 (EIF6) (C-Term) Peptide

EIF6 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN1542402
  • Target See all EIF6 products
    EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    QVLVGSYCVF SNQGGLVHPK TSIEDQDELS SLLQVPLVAG TVNRGSEVIA
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-EIF6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))
    Background
    Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits.

    Alias Symbols: 2, CAB, EIF3A, ITGB4BP, b, b(2)gcn, gcn, p27BBP, eIF-6, p27(BBP)

    Protein Interaction Partner: GNB2L1,ABCF1,ACAP3,ACTG1,AKT1S1,ALDH2,C4orf27,CRELD1,ENOX1,FUNDC2,GIT1,GNB2L1,HIP1,ITGB4,KIAA1377,LRIF1,MRPS31,OFD1,OS9,PDHA1,POLA2,PRKCB,PSME1,RPL6,SEPT3,UPF3B,USP33,WFS1,XRN2,ABCF1,ACAP3,ACTG1,AKT1S1,ALDH2,ARF6,BCCIP,C4orf27,CRELD1,EIF3B,EIF3C,EIF3J,ENO

    Protein Size: 245
    Molecular Weight
    27 kDa
    Gene ID
    3692
    NCBI Accession
    NM_002212, NP_002203
    UniProt
    P56537
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