Poly (ADP-Ribose) Polymerase 2 (PARP2) (C-Term) Peptide
PARP2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2181971
Quick Overview for Poly (ADP-Ribose) Polymerase 2 (PARP2) (C-Term) Peptide (ABIN2181971)
Target
PARP2
(Poly (ADP-Ribose) Polymerase 2 (PARP2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- QCNELLEANP KAEGLLQGKH STKGLGKMAP SSAHFVTLNG STVPLGPASD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PARP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Poly (ADP-Ribose) Polymerase 2 (PARP2) peptide
PARP2 Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
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Background
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PARP2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Alias Symbols: ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2
Protein Size: 570 -
Molecular Weight
- 62 kDa
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Gene ID
- 10038
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NCBI Accession
- NM_001042618, NP_001036083
Target
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