Histone Deacetylase 1 (HDAC1) (N-Term) Peptide
HDAC1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2182057
Quick Overview for Histone Deacetylase 1 (HDAC1) (N-Term) Peptide (ABIN2182057)
Target
HDAC1
(Histone Deacetylase 1 (HDAC1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- CYYYDGDVGN YYYGQGHPMK PHRIRMTHNL LLNYGLYRKM EIYRPHKANA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HDAC1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HDAC1 (Histone Deacetylase 1 (HDAC1))
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Background
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Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Alias Symbols: GON-10, HD1, RPD3, RPD3L1
Protein Size: 482 -
Molecular Weight
- 55 kDa
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Gene ID
- 3065
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NCBI Accession
- NM_004964, NP_004955
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UniProt
- Q13547
Target
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