Killin, p53-Regulated DNA Replication Inhibitor (KLLN) (Middle Region) Peptide
KLLN
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2182741
Quick Overview for Killin, p53-Regulated DNA Replication Inhibitor (KLLN) (Middle Region) Peptide (ABIN2182741)
Target
KLLN
(Killin, p53-Regulated DNA Replication Inhibitor (KLLN))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- DSSGGKSSSS FARGALAWCR QRNPNPSCAA AETGARTSLP KERCRGWRLG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-KLLN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KLLN (Killin, p53-Regulated DNA Replication Inhibitor (KLLN))
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Background
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The protein encoded by this intronless gene is found in the nucleus, where it can inhibit DNA synthesis and promote S phase arrest coupled to apoptosis. The expression of this DNA binding protein is upregulated by transcription factor p53.
Alias Symbols: KILLIN
Protein Size: 178 -
Molecular Weight
- 19 kDa
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Gene ID
- 100144748
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NCBI Accession
- NP_001119521
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UniProt
- B2CW77
Target
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